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Effects of caffeine on muscle signals measured with sEMG signals

Park et al. | Jun 20, 2022

Effects of caffeine on muscle signals measured with sEMG signals

Here, the authors used surface electromyography to measure the effects of caffeine intake on the resting activity of muscles. They found a significant increase in the measured amplitude suggesting that caffeine intake increased the number of activated muscle fibers during rest. While previous research has focused on caffeine's effect on the contraction signals of muscles, this research suggests that its effects extend to even when a muscle is at rest.

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Contrasting role of ASCC3 and ALKBH3 in determining genomic alterations in Glioblastoma Multiforme

Sriram et al. | Sep 27, 2022

Contrasting role of <i>ASCC3</i> and <i>ALKBH3</i> in determining genomic alterations in Glioblastoma Multiforme

Glioblastoma Multiforme (GBM) is the most malignant brain tumor with the highest fraction of genome alterations (FGA), manifesting poor disease-free status (DFS) and overall survival (OS). We explored The Cancer Genome Atlas (TCGA) and cBioportal public dataset- Firehose legacy GBM to study DNA repair genes Activating Signal Cointegrator 1 Complex Subunit 3 (ASCC3) and Alpha-Ketoglutarate-Dependent Dioxygenase AlkB Homolog 3 (ALKBH3). To test our hypothesis that these genes have correlations with FGA and can better determine prognosis and survival, we sorted the dataset to arrive at 254 patients. Analyzing using RStudio, both ASCC3 and ALKBH3 demonstrated hypomethylation in 82.3% and 61.8% of patients, respectively. Interestingly, low mRNA expression was observed in both these genes. We further conducted correlation tests between both methylation and mRNA expression of these genes with FGA. ASCC3 was found to be negatively correlated, while ALKBH3 was found to be positively correlated, potentially indicating contrasting dysregulation of these two genes. Prognostic analysis showed the following: ASCC3 hypomethylation is significant with DFS and high ASCC3 mRNA expression to be significant with OS, demonstrating ASCC3’s potential as disease prediction marker.

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Importance of pay on job satisfaction

Ravi et al. | Mar 25, 2025

Importance of pay on job satisfaction

Pay is a widely debated factor in workplace motivation, influencing both incentives and job satisfaction. This work analyzed employee reviews across various industries to examine the relationship between pay importance and job satisfaction. Findings suggest that job satisfaction decreases as the importance of pay increases, particularly in construction, food, and finance industries, as well as among entry-level and experienced workers, though the results were not statistically significant.

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Analysis of reduction potentials to determine the most efficient metals for electrochemical cell alternatives

Carroll et al. | Jul 10, 2020

Analysis of reduction potentials to determine the most efficient metals for electrochemical cell alternatives

In this study, the authors investigate what metals make the most efficient electrochemical cells, which are batteries that use the difference in electrical potential to generate electricity. Calculations predicted that a cell made of iron and magnesium would have the highest efficiency. Construction of an electrochemical cell of iron and magnesium produced voltages close to the theoretical voltage predicted. These findings are important as work continues towards making batteries with the highest storage efficiency possible.

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The Cohesiveness of the Oscillating Belousov-Zhabotinsky Reaction

Gottlieb et al. | Dec 18, 2018

The Cohesiveness of the Oscillating Belousov-Zhabotinsky Reaction

In this study the author undertakes a careful characterization of a special type of chemical reaction, called an oscillating Belousov-Zhabotinsky (or B-Z) reaction, which has a number of existing applications in biomedical engineering as well as the potential to be useful in future developments in other fields of science and engineering. Specifically, she uses experimental measurements in combination with computational analysis to investigate whether the reaction is cohesive – that is, whether the oscillations between chemical states will remain consistent or change over time as the reaction progresses. Her results indicate that the reaction is not cohesive, providing an important foundation for the development of future technologies using B-Z reactions.

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