The authors looked at whether traditional Chinese medicine remedies that target the lungs and liver would reduce inflammation in a planaria model. They found that the two active compounds they tested were able to decrease induced inflammation by 97-98%.
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TNF signaling pathway upregulation as a potential pharmaceutical target for cocaine-addicted individuals
In this article, the authors investigate the RNA expression differences between groups of chronic cocaine abusers and drug-free subjects.
Read More...Characterization of Inflammatory Cytokine Gene Expression in a Family with a History of Psoriasis
Psoriasis is a heritable autoimmune disorder characterized by abnormal red and itchy skin patches. The authors study the family of a man with psoriasis. They explore whether the man's children, who do not show any symptoms of psoriasis, demonstrate gene expression consistent with the disease.
Read More...Investigating Lymphocytic Involvement in Minimal Change Nephrotic Syndrome
Minimal Change Disease (MCD) is a degenerative kidney disease. Researchers know very little about the cause of this disorder, however some research has suggested that T lymphocytes may be involved. In this study, the authors measure CD4 and CD8 T cell subpopulations in patients with MCD to investigate whether irregular T lymphocyte populations may be involved in MCD pathogenesis.
Read More...Quantitative analysis and development of alopecia areata classification frameworks
This article discusses Alopecia areata, an autoimmune disorder causing sudden hair loss due to the immune system mistakenly attacking hair follicles. The article introduces the use of deep learning (DL) techniques, particularly convolutional neural networks (CNN), for classifying images of healthy and alopecia-affected hair. The study presents a comparative analysis of newly optimized CNN models with existing ones, trained on datasets containing images of healthy and alopecia-affected hair. The Inception-Resnet-v2 model emerged as the most effective for classifying Alopecia Areata.
Read More...Observing effects of resolving leaky gut on sugar, fat, and insulin levels during type 1 diabetes in fruit flies
This study uses a fruit fly model of type 1 diabetes (T1D) to determine whether strengthening intestinal tight junctions to reduce intestinal permeability would improve T1D symptoms.
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