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Genetic underpinnings of the sex bias in autism spectrum disorder

Lee et al. | Mar 29, 2024

Genetic underpinnings of the sex bias in autism spectrum disorder
Image credit: Louis Reed

Here, seeking to identify a possible explanation for the more frequent diagnosis of autism spectrum disorder (ASD) in males than females, they sought to investigate a potential sex bias in the expression of ASD-associated genes. Based on their analysis, they identified 17 ASD-associated candidate genes that showed stronger collective sex-dependent expression.

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POC-MON: A Novel and Cost-Effective Pocket Lemon Sniff Test (PLST) for Early Detection of Major Depressive Disorder

Cruz et al. | Jul 07, 2020

POC-MON: A Novel and Cost-Effective Pocket Lemon Sniff Test (PLST) for Early Detection of Major Depressive Disorder

Effective treatment of depression requires early detection. Depressive symptoms overlap with olfactory regions, which led to several studies of the correlation between sense of smell and depression. The alarming rise of depression, its related crimes, suicides, and lack of inexpensive, quick tools in detecting early depression — this study aims in demonstrating decreased olfaction and depression correlation. Forty-two subjects (ages 13-83) underwent POC-MON (Pocket Lemon) assessment — an oven-dried lemon peel sniff test, subjected to distance measurement when odor first detected (threshold) and completed Patient Health Questionnaires (PHQ-9). POC-MON and PHQ-9 scores yielded a correlation of 20% and 18% for the right and left nostrils, respectively. Among male (n=17) subjects, the average distance of POC-MON and PHQ-9 scores produced a correlation of 14% and 16% for the right and left nostrils, respectively. Females (n=25) demonstrated a correlation of 28% and 21% for the right and left nostrils, respectively. These results suggest the correlation between olfaction and depression in diagnosing its early-stage, using a quick, inexpensive, and patient-friendly tool — POC-MON.

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The presence of Wolbachia in Brood X cicadas

Hasan et al. | Oct 15, 2022

The presence of <em>Wolbachia</em> in Brood X cicadas

Here, seeking to understand a possible cause of the declining popluations of Brood X cicadas in Ohio and Indiana, the authors investigated the presence of Wolbachia, an inherited bacterial symbiont that lives in the reproductive cells of approximately 60% of insect species in these cicadas. Following their screening of one-hundred 17-year periodical cicadas, they only identified the presence of Wolbachia infection in less than 2%, suggesting that while Wolbachia can infect cicadas it appears uncommon in the Brood X cicadas they surveyed.

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Does Gaming Improve Cognitive Skills?

Chakravarti et al. | Jan 26, 2015

Does Gaming Improve Cognitive Skills?

Playing video games may improve mental performance by encouraging practicing logical reasoning skills. Students who played video games in between two tests tended to perform better on the second test than those that did not play video games.

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Are Age and Sex Related to Emotion Recognition Ability in Children and Teenagers?

Gallego-García et al. | Feb 23, 2018

Are Age and Sex Related to Emotion Recognition Ability in Children and Teenagers?

Humans have a natural ability to recognize emotional cues from the facial expressions of others, as a crucial evolutionary trait to navigate social interactions. This ability likely develops through normal development and social experience, but it is unclear how much influence age and sex have in emotional facial recognition (EFR). In this study, the authors investigate EFR in children and teenagers, and look at whether accurate emotional recognition does occur more in males or females.

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The juxtaposition of anatomy and physics in the eye

Zhou et al. | Oct 25, 2023

The juxtaposition of anatomy and physics in the eye

People are quick to accept the assumption that a light will appear dimmer the farther away they are, citing the inverse square relationship that illuminance obeys as rationale. However, repeated observations of light sources maintaining their brightness over large distances prompted us to explore how the brightness, or perceived illuminance of a light varies with the viewing distance from the object. We hypothesized that since both the illuminance of the light source and image size decrease at the same rate, then the concentration, or intensity of the image remains unchanged, and subsequently the perceived illuminance.

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