Browse Articles

Autologous transplantation of fresh ovarian tissue in the ICR mice model

Wang et al. | Oct 24, 2022

Autologous transplantation of fresh ovarian tissue in the ICR mice model

In this study, we performed orthotopic auto-transplantation of fresh ovarian tissues by transplanting unilateral half ovarian tissue to the contralateral ovary in the ICR (Institute of Cancer Research) strain of outbred, heterogeneous mice to determine if the transplanted tissue could be functional. We found that the freshly transplanted mouse ovarian tissue survived and functional, as histochemical and immunofluorescence assays have shown that not only both follicles at different developing stages and corpus luteum are available, but the morphology of them are properly maintained within the transplanted tissue.

Read More...

The influence of working memory on auditory category learning in the presence of visual stimuli

Vishag et al. | Sep 18, 2022

The influence of working memory on auditory category learning in the presence of visual stimuli

Here in an effort to better understand how our brains process and remember different categories of information, the authors assessed working memory capacity using an operation span task. They found that individuals with higher working memory capacity had higher overall higher task accuracy regardless of the type of category or the type of visual distractors they had to process. They suggest this may play a role in how some students may be less affected by distracting stimuli compared to others.

Read More...

Effects of Photoperiod Alterations on Stress Response in Daphnia magna

Kelly et al. | Mar 10, 2022

Effects of Photoperiod Alterations on Stress Response in <em>Daphnia magna</em>

Here, seeking to better understand the effects of altered day-night cycles, the authors considered the effects of an altered photoperiod on Daphnia magna. By tracking possible stress responses, including mean heart rate, brood size, and male-to-female ratio they found that a shorter photoperiod resulted in altered mean heart rates and brood size. The authors suggest that based on these observations, it is important to consider the effects of photoperiod alterations and the stress responses of other organisms.

Read More...

Ribosome distribution affects stalling in amino-acid starved cancer cells

Deng et al. | Jan 07, 2022

Ribosome distribution affects stalling in amino-acid starved cancer cells

In this article, the authors analyzed ribosome profiling data from amino acid-starved pancreatic cancer cells to explore whether the pattern of ribosome distribution along transcripts under normal conditions can predict the degree of ribosome stalling under stress. The authors found that ribosomes in amino acid-deprived cells stalled more along elongation-limited transcripts. By contrast, they observed no relationship between read density near start and stop and disparities between mRNA sequencing reads and ribosome profiling reads. This research identifies an important relationship between read distribution and propensity for ribosomes to stall, although more work is needed to fully understand the patterns of ribosome distribution along transcripts in ribosome profiling data.

Read More...