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Artificial intelligence assisted violin performance learning

Zhang et al. | Aug 30, 2023

Artificial intelligence assisted violin performance learning
Image credit: Philip Myrtorp

In this study the authors looked at the ability of artificial intelligence to detect tempo, rhythm, and intonation of a piece played on violin. Technology such as this would allow for students to practice and get feedback without the need of a teacher.

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Applying centrality analysis on a protein interaction network to predict colorectal cancer driver genes

Saha et al. | Nov 18, 2023

Applying centrality analysis on a protein interaction network to predict colorectal cancer driver genes

In this article the authors created an interaction map of proteins involved in colorectal cancer to look for driver vs. non-driver genes. That is they wanted to see if they could determine what genes are more likely to drive the development and progression in colorectal cancer and which are present in altered states but not necessarily driving disease progression.

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Reduce the harm of acid rain to plants by producing nitrogen fertilizer through neutralization

Xu et al. | Apr 25, 2023

Reduce the harm of acid rain to plants by producing nitrogen fertilizer through neutralization
Image credit: Ave Calvar Martinez, pexels.com

The phenomenon of dying trees and plants in areas affected by acid rain has become increasingly problematic in recent times. Is there any method to efficiently utilize the rainwater and reduce the harmfulness of acid rain or make it beneficial to plants? This study aimed to investigate the potential of neutralizing acid rainwater infiltrating the soil to increase soil pH, produce beneficial salts for plants, and support better plant growth. To test this hypothesis, precipitation samples were collected from six states in the U.S. in 2022, and the pH of the acid rain was measured to obtain a representative pH value for the country. Experiments were then conducted to simulate the neutralization of acid rain and the subsequent change in soil pH levels. To evaluate the effectiveness and feasibility of this method, cat grass was planted in pots of soil soaked with solutions mimicking acid rain, with control and experimental groups receiving neutralizing agents (ammonium hydroxide) or not. Plant growth was measured by analyzing the height of the plants. Results demonstrated that neutralizing agents were effective in improving soil pH levels and that the resulting salts produced were beneficial to the growth of the grass. The findings suggest that this method could be applied on a larger agricultural scale to reduce the harmful effects of acid rain and increase agricultural efficiency.

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Machine learning-based enzyme engineering of PETase for improved efficiency in plastic degradation

Gupta et al. | Jan 31, 2023

 Machine learning-based enzyme engineering of PETase for improved efficiency in plastic degradation
Image credit: Markus Spiske

Here, recognizing the recognizing the growing threat of non-biodegradable plastic waste, the authors investigated the ability to use a modified enzyme identified in bacteria to decompose polyethylene terephthalate (PET). They used simulations to screen and identify an optimized enzyme based on machine learning models. Ultimately, they identified a potential mutant PETases capable of decomposing PET with improved thermal stability.

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Exploring natural ways to maintain keratin production in hair follicles

Roy et al. | Apr 29, 2024

Exploring natural ways to maintain keratin production in hair follicles
Image credit: Roy and Roy, 2024

We are looking into natural ways to help hair grow better and stronger by studying keratin synthesis in human hair follicles. The reason for conducting this research was to have the ability to control hair growth through future innovations. We wanted to answer the question: How can we find natural ways to enhance hair growth by understanding the connection with natural resources, particularly keratin dynamics? The main focus of this experiment is understanding the promotion of keratin synthesis within human hair follicles, which is important for hair development and health. While keratin is essential for the growth and strength of body tissues, including skin and hair, our research hints at its specific synthesis within hair follicles. In our research utilizing castor oil, coconut oil, a turmeric and baking soda mixture, and a sugar, honey, and lemon mixture, we hypothesize that oils, specifically coconut oil and castor oil, will enhance keratin synthesis, whereas mixtures, such as the turmeric and baking soda mixture and the sugar, honey, and lemon mixture, will result in a decrease keratin synthesis. The methods used show how different natural substances influence keratin formation within the hair follicles. The experiment involved applying natural resources to hair strands and follicles, measuring their length under the microscope daily, and assessing their health and characteristics over seven days. In summary, our research helps us understand how hair grows better. We found that using natural items like essential oils effectively alters keratin growth within the hair follicles and hair strands.

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Artificial Intelligence Networks Towards Learning Without Forgetting

Kreiman et al. | Oct 26, 2018

Artificial Intelligence Networks Towards Learning Without Forgetting

In their paper, Kreiman et al. examined what it takes for an artificial neural network to be able to perform well on a new task without forgetting its previous knowledge. By comparing methods that stop task forgetting, they found that longer training times and maintenance of the most important connections in a particular task while training on a new one helped the neural network maintain its performance on both tasks. The authors hope that this proof-of-principle research will someday contribute to artificial intelligence that better mimics natural human intelligence.

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Using explainable artificial intelligence to identify patient-specific breast cancer subtypes

Suresh et al. | Jan 12, 2024

Using explainable artificial intelligence to identify patient-specific breast cancer subtypes

Breast cancer is the most common cancer in women, with approximately 300,000 diagnosed with breast cancer in 2023. It ranks second in cancer-related deaths for women, after lung cancer with nearly 50,000 deaths. Scientists have identified important genetic mutations in genes like BRCA1 and BRCA2 that lead to the development of breast cancer, but previous studies were limited as they focused on specific populations. To overcome limitations, diverse populations and powerful statistical methods like genome-wide association studies and whole-genome sequencing are needed. Explainable artificial intelligence (XAI) can be used in oncology and breast cancer research to overcome these limitations of specificity as it can analyze datasets of diagnosed patients by providing interpretable explanations for identified patterns and predictions. This project aims to achieve technological and medicinal goals by using advanced algorithms to identify breast cancer subtypes for faster diagnoses. Multiple methods were utilized to develop an efficient algorithm. We hypothesized that an XAI approach would be best as it can assign scores to genes, specifically with a 90% success rate. To test that, we ran multiple trials utilizing XAI methods through the identification of class-specific and patient-specific key genes. We found that the study demonstrated a pipeline that combines multiple XAI techniques to identify potential biomarker genes for breast cancer with a 95% success rate.

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Assessing and Improving Machine Learning Model Predictions of Polymer Glass Transition Temperatures

Ramprasad et al. | Mar 18, 2020

Assessing and Improving Machine Learning Model Predictions of Polymer Glass Transition Temperatures

In this study, the authors test whether providing a larger dataset of glass transition temperatures (Tg) to train the machine-learning platform Polymer Genome would improve its accuracy. Polymer Genome is a machine learning based data-driven informatics platform for polymer property prediction and Tg is one property needed to design new polymers in silico. They found that training the model with their larger, curated dataset improved the algorithm's Tg, providing valuable improvements to this useful platform.

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