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Motion tracking and analysis of spray water droplets studied by high-speed photography using an iPhone X

Geng et al. | Sep 11, 2021

Motion tracking and analysis of spray water droplets  studied by high-speed photography using an iPhone X

Smartphones are not only becoming an inseparable part of our daily lives, but also a low-cost, powerful optical imaging tool for more and more scientific research applications. In this work, smartphones were used as a low-cost, high-speed, photographic alternative to expensive equipment, such as those typically found in scientific research labs, to accurately perform motion tracking and analysis of fast-moving objects. By analyzing consecutive images, the speed and flight trajectory of water droplets in the air were obtained, thereby enabling us to estimate the area of the water droplets landing on the ground.

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Effects of Prolonged Azithromycin Therapy on Bacterial Resistance to Functionally Analogous Antibiotics

Gibbs et al. | Dec 04, 2020

Effects of Prolonged Azithromycin Therapy on Bacterial Resistance to Functionally Analogous Antibiotics

In this study, the authors investigate a potential case of cross antibiotic-resistance. Using swabs from an individual who received long-term treatments of azithromycin, they addressed the question of whether any bacteria in this individual might develop resistance to not only azithromycin, but also other antibiotics with similar structures. This study cleverly addresses the important issue of antibiotic resistance from a new and thoughtful approach.

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Culturally Adapted Assessment Tool for Autism Spectrum Disorder and its Clinical Significance

Das et al. | Apr 19, 2021

Culturally Adapted Assessment Tool for Autism Spectrum Disorder and its Clinical Significance

Diagnosing of Autism Spectrum Disorder (ASD) using tools developed in the West is challenging in the Indian setting due to a huge diversity in sociocultural and economic backgrounds. Here, the authors developed a home-based, audiovisual game app (Autest) suitable for ASD risk assessment in Indian children under 10 years of age. Ratings suggested that the tool is effective and can reduce social inhibition and facilitate assessment. Further usage and development of Autest can improve risk assessment and early intervention measures for children with ASD in India.

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Effect of hypervitaminosis A in regenerating planaria: A potential model for teratogenicity testing

Bennet et al. | Dec 12, 2022

Effect of hypervitaminosis A in regenerating planaria: A potential model for teratogenicity testing

This unique research study evaluated the potential use of the flatworm, brown planaria (Dugesia tigrine), as an alternative model for teratogenicity testing. In this study, we exposed amputated planaria to varying concentrations of a known teratogen, vitamin A (retinol), for approximately 2 weeks, and evaluated multiple parameters including the formation of blastema and eyes. The results from this study demonstrated that high concentrations of retinol caused defects in head and eye formation in regenerating planaria, with similarities to vitamin A related teratogenicity findings in mammals. Based on these results, regenerating brown planaria are a promising alternative model for teratogenicity testing, which can potentially be paradigm shifting as it can reduce cost, time, and pregnant animal use in research.

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A Simple Printing Solution to Aid Deficit Reduction

Mirchandani et al. | Mar 09, 2014

A Simple Printing Solution to Aid Deficit Reduction

The printing-related expenditure that is budgeted in 2014 for U.S. Federal agencies is $1.8 billion. A sample of five publically available documents produced by various federal agencies is analyzed and the cost savings arising from a change in font type are estimated. The analysis predicts that the Government’s annual savings by switching to Garamond are likely to be about $234 million with worst-case savings of $62 million and best-case savings of $394 million. Indirect benefits arising from a less detrimental impact on the environment due to lower ink production and disposal volumes are not included in these estimates. Times New Roman is not as efficient as Garamond, and the third federally-recommended font, Century Gothic, is actually worse on average than the fonts used in the sample documents.

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Optical anisotropy of crystallized vanillin thin film: the science behind the art

Wang et al. | Jul 09, 2024

Optical anisotropy of crystallized vanillin thin film: the science behind the art
Image credit: The authors

Microscopic beauty is hiding in common kitchen ingredients - even vanillin flavoring can be turned into mesmerizing artwork by crystallizing the vanillin and examining it under a polarizing microscope. Wang and Pang explore this hidden beauty by determining the optimal conditions to grow crystalline vanillin films and by creating computer simulations of chemical interactions between vanillin molecules.

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Fractal dimensions of crumpled paper

Zhou et al. | Aug 10, 2023

Fractal dimensions of crumpled paper
Image credit: Richard Dykes

Here, beginning from an interest in fractals, infinitely complex shapes. The authors investigated the fractal object that results from crumpling a sheet of paper. They determined its fractal dimension using continuous Chi-squared analysis, thereby testing and validating their model against the more conventional least squares analysis.

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Identification of microwave-related changes in tissue using an ultrasound scan

Shariff et al. | Apr 24, 2024

Identification of microwave-related changes in tissue using an ultrasound scan
Image credit: Shariff and Shariff 2024

Microwave energy (ME) is used in the medical field to denature protein structures, resulting in inactivation or destruction of abnormal cells. Identifying the extent of destruction of abnormal tissue (cancer tissue or tissue with abnormal electrical activity) is essential for accomplishing successful therapy and reducing collateral damage. Our study was an ex vivo assessment of the changes on ultrasound scans (US) in chicken tissue exposed to ME. We hypothesized that any changes in tissue structures would be recognized on the reflected ultrasound waves. Ultrasound scans of tissues change with exposure to microwaves with increasing reflection of ultrasound waves. With exposure to microwaves, surface level brightness on the ultrasound scans increases statistically significantly. The findings could be used in heat related (ME and radiofrequency) procedures where clinicians would be able to actively assess lesions in real-time. Further studies are required to assess changes in tissue during active exposure to different types of energies.

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Singlet oxygen production analysis of reduced berberine analogs via NMR spectroscopy

Su et al. | Feb 10, 2023

Singlet oxygen production analysis of reduced berberine analogs via NMR spectroscopy

Berberine is a natural product isoquinoline alkaloid derived from plants of the genus Berberis. When exposed to photoirradiation, it produces singlet oxygen through photosensitization of triplet oxygen. Through qNMR analysis of 1H NMR spectra gathered through kinetic experiments, we were able to track the generation of a product between singlet oxygen and alpha terpinene, allowing us to quantitatively measure the photosensitizing properties of our scaffolds.

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