UV-B radiation due to the depletion of ozone threatens plant life, potentially damaging ecosystems and dismantling food webs. Here, the impact of UV-B radiation on the physiology and morphology of Allum cepa, the common onion, was assessed. Mitosis vitality decreased, suggesting UV-B damage can influence the plant’s physiology.
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The Protective Effects of Panax notoginseng Saponin on the Blood-Brain Barrier via the Nrf2/ARE Pathway in bEnd3 Cells
Disruption of the blood-brain barrier (BBB) is related to many neurological disorders, and can be caused by oxidative stress to cerebral microvascular endothelial cells (CMECs) composing the BBB. The authors of the paper investigated the protective effects of the total saponins in the leaves of Panax notoginseng (LPNS) on oxidative-stress-induced damage in a mouse cerebral microvascular endothelial cell line.
Read More...An in vitro comparative analysis of the growth factors present in FBS vs PLAY®
Here the authors performed a comparative analysis to investigate the viability of using PLAY® instead of fetal bovine serum (FBS) as a growth medium to culture cells with an enzyme-linked immunosorbent assay.
Read More...Temporal characterization of electroencephalogram slowing activity types
The authors use machine learning to analyze electroencephalogram data and identify slowing patterns that can indicate undetected disorders like epilepsy or dementia
Read More...Mendelian randomization reveals shared genetic landscape in autism spectrum disorder and Alzheimer's disease
Autism Spectrum Disorder (ASD) and Alzheimer's Disease (AD) are distinct conditions, but research suggests a link, as individuals with ASD are 2.5 times more likely to develop AD. A study employing genome-wide association studies and Mendelian randomization revealed shared genetic factors, particularly in synaptic regulation pathways, that may increase the risk of AD in those with ASD. These findings provide insights into the genetic underpinnings connecting the two disorders.
Read More...Reduced psoriasis skin irritation symptoms through the effects of Chinese herbal medicines on planarians
The authors looked at whether traditional Chinese medicine remedies that target the lungs and liver would reduce inflammation in a planaria model. They found that the two active compounds they tested were able to decrease induced inflammation by 97-98%.
Read More...Parental exposure of cannabinoids THC and CBD reduces reproductive rates in Drosophila melanogaster
The authors looked at whether CBD and THC would decrease reproductive rates in a Drosophila melanogaster model. They found that CBD had a greater impact on reducing hatching rates than THC, and that THC resulted in unexpected mortalities.
Read More...Genetic underpinnings of the sex bias in autism spectrum disorder
Here, seeking to identify a possible explanation for the more frequent diagnosis of autism spectrum disorder (ASD) in males than females, they sought to investigate a potential sex bias in the expression of ASD-associated genes. Based on their analysis, they identified 17 ASD-associated candidate genes that showed stronger collective sex-dependent expression.
Read More...Investigating the impact of electrocardiography biofeedback on POTS symptom management
The authors test electrocardiography biofeedback as a treatment for individuals with Postural Orthostatic Tachycardia Syndrome.
Read More...Varying levels of disinfectant resistance among invasive Klebsiella pneumoniae isolates
The authors identify disinfectant-resistant bacterial strains of infection-causing bacteria from samples collected at a hospital setting.
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