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Impact of gadodiamide (Omniscan) on a beef liver catalase ex vivo model

Hirsch et al. | Mar 10, 2023

Impact of gadodiamide (Omniscan) on a beef liver catalase <em>ex vivo</em> model
Image credit: Marcelo Leal

Here, seeking to better understand the effects of gadolinium-based contrast agents, dyes typically used for MRI scans, the authors evaluated the activity of catalase found in beef liver both with and without gadodiamide when exposed to hydrogen peroxide. They found that gadioamide did not significantly inhibit catalase's activity, attributing this lack of effects to the chelating agent found in gadodiamide.

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Investigating the Role of the Novel ESCRT-III Recruitment Factor CCDC11 in HIV Budding: A Potential Target for Antiviral Therapy

Takemaru et al. | Feb 24, 2020

Investigating the Role of the Novel ESCRT-III Recruitment Factor CCDC11 in HIV Budding: A Potential Target for Antiviral Therapy

Acquired immunodeficiency syndrome (AIDS) is a life-threatening condition caused by the human immunodeficiency virus (HIV). In this work, Takemaru et al explored the role of Coiled-Coil Domain-Containing 11 (CCDC11) in HIV-1 budding. Their results suggest that CCDC11 is critical for efficient HIV-1 budding, potentially indicating CCDC11 a viable target for antiviral therapeutics without major side effects.

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Don’t Waste the Medical Waste: Reducing Improperly Classified Hazardous Waste in a Medical Facility

Hemani et al. | Jun 20, 2018

Don’t Waste the Medical Waste: Reducing Improperly Classified Hazardous Waste in a Medical Facility

Hemani et al. tackled the problem of rampant hospital waste by implementing staff training to help inform hospital workers about proper waste disposal. The authors observed a significant increase in proper waste disposal after the training, showing that simple strategies, such as in-person classroom training and posters, can have a profound effect on limiting improper waste handling.

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Utilizing a novel T1rho method to detect spinal degeneration via magnetic resonance imaging

Wang et al. | Oct 04, 2023

Utilizing a novel T1rho method to detect spinal degeneration via magnetic resonance imaging

Spinal degeneration has been linked to critical conditions such as osteoarthritis in adults aged 40+; while this condition is considered to be irreversible, we took interest in magnetic resonance imaging (MRI) for early detection of the condition. Ultimately, our purpose was to determine the effectiveness of a relatively novel T1rho method in the early detection of spinal degeneration, and we hypothesized that the early to mild progression of spinal degeneration would affect T1rho values following an MRI scan.

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Using economic indicators to create an empirical model of inflation

Kasera et al. | Dec 01, 2022

Using economic indicators to create an empirical model of inflation

Here, seeking to understand the correlation of 50 of the most important economic indicators with inflation, the authors used a rolling linear regression to identify indicators with the most significant correlation with the Month over Month Consumer Price Index Seasonally Adjusted (CPI). Ultimately the concluded that the average gasoline price, U.S. import price index, and 5-year market expected inflation had the most significant correlation with the CPI.

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