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Fluorescein or Green Fluorescent Protein: Is It Possible to Create a Sensor for Dehydration?

Joshi et al. | Dec 09, 2019

Fluorescein or Green Fluorescent Protein: Is It Possible to Create a Sensor for Dehydration?

Currently there is no early dehydration detection system using temperature and pH as indicators. A sensor could alert the wearer and others of low hydration levels, which would normally be difficult to catch prior to more serious complications resulting from dehydration. In this study, a protein fluorophore, green fluorescent protein (GFP), and a chemical fluorophore, fluorescein, were tested for a change in fluorescence in response to increased temperature or decreased pH. Reversing the pH change did not restore GFP fluorescence, but that of fluorescein was re-established. This finding suggests that fluorescein could be used as a reusable sensor for a dehydration-related pH change.

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Giving Teens a Voice: Sources of Stress for High School Students

Corson et al. | Sep 09, 2019

Giving Teens a Voice: Sources of Stress for High School Students

The authors investigate the negative effects stress has on teen mental and physical health. Through a survey, they give Virginia teens a voice in revising the Health and Physical Education curriculum to include a standards of learning (SOL). Notably they identify factors contributing to stress levels including homework level, amount of free and sleep time, parental pressure and family encouragement.

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Specific Transcription Factors Distinguish Umbilical Cord Mesenchymal Stem Cells From Fibroblasts

Park et al. | Aug 16, 2019

Specific Transcription Factors Distinguish Umbilical Cord Mesenchymal Stem Cells From Fibroblasts

Stem cells are at the forefront of research in regenerative medicine and cell therapy. Two essential properties of stem cells are self-renewal and potency, having the ability to specialize into different types of cells. Here, Park and Jeong took advantage of previously identified stem cell transcription factors associated with potency to differentiate umbilical cord mesenchymal stem cells (US-MSCs) from morphologically similar fibroblasts. Western blot analysis of the transcription factors Klf4, Nanog, and Sox2 revealed their expression was unique to US-MSCs providing insight for future methods of differentiating between these cell lines.

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The Effects of Altered Microbiome on Caenorhabditis elegans Egg Laying Behavior

Gohari et al. | Aug 12, 2019

The Effects of Altered Microbiome on <em>Caenorhabditis elegans</em> Egg Laying Behavior

Since the discovery that thousands of different bacteria colonize our gut, many of which are important for human wellbeing, understanding the significance of balancing the different species on the human body has been intensely researched. Untangling the complexity of the gut microbiome and establishing the effect of the various strains on human health is a challenge in many circumstances, and the need for simpler systems to improve our basic understanding of microbe-host interactions seems necessary. C. elegans are a well-established laboratory animal that feed on bacteria and can thus serve as a less complex system for studying microbe-host interactions. Here the authors investigate how the choice of bacterial diet affects worm fertility. The same approach could be applied to many different outcomes, and facilitate our understanding of how the microbes colonizing our guts affect various bodily functions.

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Measuring Exoplanetary Radii Using Transit Photometry

Tang et al. | May 07, 2019

Measuring Exoplanetary Radii Using Transit Photometry

Studying exoplanets, or planets that orbit a star other than the Sun, is critical to a greater understanding the formation of planets and how Earth's solar system differs from others. In this study the authors analyze the transit light curves of three hot Jupiter exoplanets to ultimately determine if and how these planets have changed since their discovery.

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The Effects of Post-Consumer Waste Polystyrene on the Rate of Mealworm Consumption

Green et al. | Nov 29, 2018

The Effects of Post-Consumer Waste Polystyrene on the Rate of Mealworm Consumption

In a world where plastic waste accumulation is threatening both land and sea life, Green et al. investigate the ability of mealworms to breakdown polystyrene, a non-recyclable form of petrochemical-based polymer we use in our daily lives. They confirm that these organisms, can degrade various forms of polystyrene, even after it has been put to use in our daily lives. Although the efficiency of the degradation process still requires improvement, the good news is, the worms are tiny and themselves are biodegradable, so we can use plenty of them without worrying about space and how to get rid of them. This is very promising and certainly good news for the planet.

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Optimizing Interplanetary Travel Using a Genetic Algorithm

Murali et al. | Oct 28, 2018

Optimizing Interplanetary Travel Using a Genetic Algorithm

In this work, the authors develop an algorithm that solves the problem of efficient space travel between planets. This is a problem that could soon be of relevance as mankind continues to expand its exploration of outer space, and potentially attempt to inhabit it.

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A Novel Method for Assessment of Proprioception

Trevithick et al. | Jun 22, 2018

A Novel Method for Assessment of Proprioception

Trevithick & Park were interested in whether proprioception, the sense of the relative position of body parts and movement, differed between varsity and non-varsity athletes, as well as between the sport practiced. The authors found that there was no correlation between athleticism and better proprioception, but that dancers had superior proprioceptive abilities compared to those that practiced other sports.

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