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The Effects of Barley Straw (Hordeum vulgare) Extract and Barley Straw Pellets on Algal Growth and Water Quality

McHargue et al. | Oct 06, 2020

The Effects of Barley Straw (Hordeum vulgare) Extract and Barley Straw Pellets on Algal Growth and Water Quality

Algal overgrowth often threatens to clog irrigation pipes and drinking water lines when left unchecked, as well as releasing possible toxins that threaten plant and human health. It is thus important to find natural, non-harmful agents that can decrease algal growth without threatening the health of plants and humans. In this paper, the authors test the efficacy of barely extract in either liquid or pellet form in decreasing algal growth. While their results were inconclusive, the experimental set-up allows them to investigate a wider range of agents as anti-algal treatments that could potentially be adopted on a wider scale.

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The Protective Antioxidant Effects of Sulforaphane on Germinating Radish Seeds Treated with Hydrogen Peroxide

Dasuri et al. | Feb 19, 2021

The Protective Antioxidant Effects of Sulforaphane on Germinating Radish Seeds Treated with Hydrogen Peroxide

Free radical chain reactions result when atoms containing unpaired electrons bind with biomolecules and alter their biological functions, contributing to the progression of diseases such as atherosclerosis, cancer, and diabetes. Antioxidants, such as vitamin E and sulforaphane, are effective neutralizers of free radicals and prevent cellular damage. This present study is conducted to determine the relative effectiveness of sulforaphane against free radicals generated by hydrogen peroxide (H2O2) compared with the known antioxidant vitamin E.

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Cytokine Treatment for Myocarditis May Directly Impact Cardiomyocytes Negatively

Kasner et al. | Apr 26, 2019

Cytokine Treatment for Myocarditis May Directly Impact Cardiomyocytes Negatively

The purpose of our study was to determine if direct administration of CXCL1/KC to cardiomyocytes causes negative changes to cell density or proliferation. This molecule has been shown to reduce inflammation in certain instances. Homocysteine models the direct effect of an inflammatory agent on cardiomyocytes. Our question was whether these molecules directly impact cell density through an interaction with the cell proliferation process. We hypothesized that cells treated with CXCL1/KC would maintain the same cell density as untreated cells. In contrast, cells treated with Homocysteine or both Homocysteine and CXCL1/KC, were expected to have a higher cell density that than that of untreated cells.

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A new hybrid cold storage material

Zhang et al. | Jun 05, 2022

A new hybrid cold storage material

With low-temperature transportation being critical for the progress of research and medical services by preserving biological samples and vaccines, the optimization of cold storage materials is more critical now than ever. The exclusive use of dry ice has its limitations. Notably, it proves insufficient for cold storage during long-range transportation necessary for the delivery of specimens to rural areas. In this article, the authors have proposed a new means of cold storage through the combination of dry ice and ethanol. Upon thorough analysis, the authors have determined their new method as considerably better than the use of pure dry ice across many characteristics, including cold storage capacity, longevity of material, and financial and environmental feasibility.

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The Role of a Mask - Understanding the Performance of Deep Neural Networks to Detect, Segment, and Extract Cellular Nuclei from Microscopy Images

Dasgupta et al. | Jul 06, 2021

The Role of a Mask - Understanding the Performance of Deep Neural Networks to Detect, Segment, and Extract Cellular Nuclei from Microscopy Images

Cell segmentation is the task of identifying cell nuclei instances in fluorescence microscopy images. The goal of this paper is to benchmark the performance of representative deep learning techniques for cell nuclei segmentation using standard datasets and common evaluation criteria. This research establishes an important baseline for cell nuclei segmentation, enabling researchers to continually refine and deploy neural models for real-world clinical applications.

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Anticancer, anti-inflammatory, and apoptotic activities of MAT20, a poly-herbal formulation.

Kashyap Jha et al. | Mar 29, 2022

Anticancer, anti-inflammatory, and apoptotic activities of MAT20, a poly-herbal formulation.

Kashyap Jha et al. look at the formulation of MAT20, a crude extract of the moringa, amla, and tulsi leaves, as a potential complementary and alternative medicine. Using HeLa cells, they find MAT20 up-regulates expression of inflammation and cell cytotoxicity markers. Their data is important for understanding the anti-cancer and anti-inflammatory properties of MAT20.

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Comparing the effects of electronic cigarette smoke and conventional cigarette smoke on lung cancer viability

Choe et al. | Sep 18, 2022

Comparing the effects of electronic cigarette smoke and conventional cigarette smoke on lung cancer viability

Here, recognizing the significant growth of electronic cigarettes in recent years, the authors sought to test a hypothesis that three main components of the liquid solutions used in e-cigarettes might affect lung cancer cell viability. In a study performed by exposing A549 cells, human lung cancer cells, to different types of smoke extracts, the authors found that increasing levels of nicotine resulted in improve lung cancer cell viability up until the toxicity of nicotine resulted in cell death. They conclude that these results suggest that contrary to conventional thought e-cigarettes may be more dangerous than tobacco cigarettes in certain contexts.

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A study to determine the anti-cancer and pro-apoptotic properties of Amaranthus spinosus Linn. Extract, AS20

Sharma et al. | Nov 24, 2020

A study to determine the anti-cancer and pro-apoptotic properties of Amaranthus spinosus Linn. Extract, AS20

In this study, the authors investigate whether a new compound has anti-cancer properties. Using the crude extract from the Amaranthus spinosus plant, HeLa cancer cells were assessed for cell death. Findings reveal that the extract (AS20) has cytotoxic effects on HeLa cells. Their findings introduce a new compound to potentially pursue in the hunt for novel cancer treatments.

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Herbal formulation, HF1 diminishes tumorigenesis: a cytokine study between MCF-7 and BM-MSCs.

Guru et al. | Apr 11, 2022

Herbal formulation, HF1 diminishes tumorigenesis: a cytokine study between MCF-7 and BM-MSCs.

The authors use HF-1, an herbal formation, on bone marrow derived cells as well as breast cancer cells to assess HF-1's ability to prevent tumorigenesis. As metastasis requires coordination of multiple cells in the tumor microenvironment, their findings that HF-1 augments cytokine expression such as VEGF & TGF-B show that HF-1 has potential application to therapeutics.

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