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The Effect of Ultraviolet Radiation and the Antioxidant Curcumin on the Longevity, Fertility, and Physical Structure of Drosophila melanogaster: Can We Defend Our DNA?

Lateef et al. | May 18, 2019

The Effect of Ultraviolet Radiation and the Antioxidant Curcumin on the Longevity, Fertility, and Physical Structure of <em>Drosophila melanogaster</em>: Can We Defend Our DNA?

Ultraviolet (UV) radiation is known to alter DNA structure and impair cellular function in all living organisms. In this study, Lateef et al examine the effects of UV radiation to determine whether antioxidant-enriched nutrition can combat the potential deleterious effects of UV radiation on Drosophila melanogaster. They found that UVB (320nm) radiation caused a 59% decrease in the Drosophila lifespan and mutagenic effects on flies' physical appearance, but did not significantly affect fertility. Curcumin significantly prolonged lifespan and enhanced fertility for both UV- and non-UV-exposed flies. The research demonstrates the positive potential of natural antioxidants as weapons against radiation-induced diseases including cancer.

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The external presence of running water influences the root growth of pea plants (Phaselous vulgaris)

Shu et al. | Nov 10, 2020

The external presence of running water influences the root growth of pea plants (Phaselous vulgaris)

Each year, invasive tree roots cause large amounts of damage to underground pipes. While this is usually due to leaks and cracks, tree roots can also invade pipes that are structurally sound. We are interested in investigating whether plant roots have an affinity towards flowing water, measured through mass, even when the running water is not in direct contact with soil. We tested this by creating a choice chamber with water running under one end and no stimulus on the other end. Overall, the masses of the roots growing towards flowing water were greater than the masses of the roots growing towards the end with no stimulus, showing that plant roots did have an affinity towards flowing water.

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How planarians are affected by mouthwash and cough syrup

Mebane et al. | Nov 14, 2021

How planarians are affected by mouthwash and cough syrup

Since cough syrup and mouthwash are commonly used items and often end up flushed down the drain or toilet, they can eventually find their way into into freshwater waterways which can be harmful to many marine organisms, such as planarians (aquatic flatworms). To investigate the effects of these substances on planarians, the authors considered different concentrations of Listerine mouthwash and Robitussin syrup along with their active ingredients. By using a behavioral assay, they identified that the active ingredients of cough syrup detrimentally affect planarian behavior. They suggest that these findings could be used to guide disposal methods to lessen detrimental effects on aquatic life.

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Testing the Effects of Resveratrol, Apigenin, and Glucosamine to Effectively Reduce Prostate Cancer Cell Proliferation, Migration Levels, and Increase Apoptosis

Yang et al. | Apr 16, 2020

Testing the Effects of Resveratrol, Apigenin, and Glucosamine to Effectively Reduce Prostate Cancer Cell Proliferation, Migration Levels, and Increase Apoptosis

The current five-year survival rate of metastasized prostate cancer is only 30% and occurs in every one in nine men. Researchers have shown that people with a type of dwarfism called Laron’s Syndrome are immune to cancer due to their low levels of insulin-like growth factor-1 (IGF-1). For this reason, experimentally modifying the level of IGF-1 could provide better insight into whether lowering the levels of IGF-1 in prostate cancer cell lines (e.g. PC-3) could be an effective treatment to reduce their rates of proliferation and migration and increase apoptosis. We selected three compounds, which researchers have shown decrease IGF-1 levels, to test and combine to determine which is the most promising.

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The Effect of Anubias barteri Plant Species on Limiting Freshwater Acidification

Ramanathan et al. | Jul 06, 2021

The Effect of <i>Anubias barteri</i> Plant Species on Limiting Freshwater Acidification

Research relating to freshwater acidification is minimal, so the impact of aquatic plants, Anubias barteri var. congensis and Anubias barteri var. nana, on minimizing changes in pH was explored in an ecosystem in Northern California. Creek water samples, with and without the aquatic plants, were exposed to dry ice to simulate carbon emissions and the pH was monitored over an eight-hour period. There was a 25% difference in the observed pH based on molar hydrogen ion concentration between the water samples with plants and those without plants, suggesting that aquatic plants have the potential to limit acidification to some extent. These findings can guide future research to explore the viable partial solution of aquatic plants in combating freshwater acidification.

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Aggression of Carcharhinus leucas and Carcharhinus amblyrhynchos towards humans

Mignone et al. | May 11, 2021

Aggression of <i>Carcharhinus leucas</i> and <i>Carcharhinus amblyrhynchos</i> towards humans

This paper presents findings on Carcharhinus leucas (bull shark) and Carcharhinus amblyrhynchos (grey reef shark) aggression towards humans at Beqa Adventure Divers in Shark Reef Marine Reserve, Fiji. We hypothesized that grey reef sharks would receive more prods than bull sharks because grey reef sharks are typically more aggressive than bull sharks. The results supported our hypothesis, as an individual grey reef shark received 2.44 prods on average per feed, while a bull shark had an average of 0.61. These findings are meaningful not only to the world’s general understanding of shark aggression, but also to human protection against grey reef sharks as well as public education on bull sharks and the conservation of the species.

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Wound healing properties of mesenchymal conditioned media: Analysis of PDGF, VEGF and IL-8 concentrations

Prasad et al. | Dec 15, 2021

Wound healing properties of mesenchymal conditioned media: Analysis of PDGF, VEGF and IL-8 concentrations

Regenerative medicine has become a mainstay in recent times, and employing stem cells to treat several degenerative, inflammatory conditions has resulted in very promising outcomes. These forms of cell-based therapies are novel approaches to existing treatment modalities. In this study, the authors compared the concentrations of the cytokines PDGF, IL-8, and VEGF between conditioned and spent media of mesenchymal stem cells (MSCs) to evaluate their potential therapeutic properties for wound healing in inflammatory conditions. They hypothesized that conditioned media contains higher concentrations of wound healing cytokines compared to spent media. The authors found that while IL-8 and VEGF were present in highest concentrations in conditioned media, PDGF was present in maximal amounts in spent media.

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Access to public parks, drinking fountains, and clean public drinking water in the Bay Area is not driven by income

Zaroff et al. | Jul 15, 2021

Access to public parks, drinking fountains, and clean public drinking water in the Bay Area is not driven by income

Access to green space—an area of grass, trees, or other vegetation set apart for recreational or aesthetic purposes in an urban environment—and clean drinking water can be unequally distributed in urban spaces, which are often associated with income inequality. Little is known about public drinking water and green space inequities in the Bay Area. For our study, we sought to understand how public park access, drinking fountain access, and the quality of public drinking water differ across income brackets in the Bay Area. Though we observed smaller-scale instances of inequalities, in the park distribution in the Bay Area as a whole, and in the Southern Bay’s water quality and park distribution, our results indicate that other factors could be influencing water quality, and park and fountain access in the Bay Area.

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Attitudes towards mental health in Indians who practice yoga regularly and those who do not

Komar et al. | Jul 13, 2022

Attitudes towards mental health in Indians who practice yoga regularly and those who do not

Whether it is through implicit association or intentional practice, yoga has been known to help individuals maintain good mental health. However, many communities, such as South Asian communities, often project the stereotype that embodies neglecting topics such as mental health and considering them taboo. In this online survey-based study, the authors focused on examining whether yoga would alter individuals’ attitudes toward mental health. They hypothesized that 1) participants who regularly practiced yoga would be more familiar with the term mental health, 2) participants who practiced yoga would value their mental health more, and 3) participants who practiced yoga regularly would be more open about their mental health and be more likely to reach out for professional help if needed. They did not find a statistical significance for any of our hypotheses which suggests that yoga may not have an effect on perceptions of mental health in yoga-practicing Indian adults.

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Differential privacy in machine learning for traffic forecasting

Vinay et al. | Dec 21, 2022

Differential privacy in machine learning for traffic forecasting

In this paper, we measured the privacy budgets and utilities of different differentially private mechanisms combined with different machine learning models that forecast traffic congestion at future timestamps. We expected the ANNs combined with the Staircase mechanism to perform the best with every value in the privacy budget range, especially with the medium high values of the privacy budget. In this study, we used the Autoregressive Integrated Moving Average (ARIMA) and neural network models to forecast and then added differentially private Laplacian, Gaussian, and Staircase noise to our datasets. We tested two real traffic congestion datasets, experimented with the different models, and examined their utility for different privacy budgets. We found that a favorable combination for this application was neural networks with the Staircase mechanism. Our findings identify the optimal models when dealing with tricky time series forecasting and can be used in non-traffic applications like disease tracking and population growth.

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