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Each year, over 100,000 patients die from Sudden Unexpected Death in Epilepsy (SUDEP). A reliable seizure warning system can help patients stay safe. This work presents a comprehensive, comparative analysis of three different signal processing algorithms for automated seizure/ictal detection. The experimental results show that the proposed methods can be effective for accurate automated seizure detection and monitoring in clinical care.

Ischemic stroke occurs when blood flow to the brain is interrupted, causing brain damage. This study investigated the effectiveness of different NOX inhibitors as treatments for ischemic stroke in silico. The results help corroborate previous in vivo and in vitro studies in an in silico format, and can be used towards developing drugs to treat ischemic stroke.

Manufacturers that produce products using fused filament fabrication (FFF) 3D printing technologies have control of numerous build parameters. This includes the number of solid layers on the exterior of the product, the percentage of material filling the interior volume, and the many different types of infill patterns used to fill their interior.This study investigates the hypothesis that as the density of the part increases, the mechanical properties will improve at the expense of build time and the amount of material required.

Evidence supports that spiders have many ecological benefits including insect control and predation in the food chain. In this study the authors investigate that whether the percent of vegetation coverage and spider density are correlated. They determine that despite the trend there is no statistically significant correlation.

Muons, one of the fundamental elementary particles, originate from the collision of cosmic rays with atmospheric particles and are also generated in particle accelerator collisions. In this study, Samson et al analyze the factors that influence muon flux and lifetime using Cosmic Ray Muon Detectors (CRMDs). Overall, the study suggests that water can be used to decrease muon flux and that scintillator orientation is a potential determinant of the volume of data collected in muon decay studies.

High-fructose diets consumed widely in modern societies predisposes to metabolic diseases such as diabetes. Using the worm C. elegans, the authors of this study investigated the effect of fructose on the worm's survival rates. They found that worms fed 15% fructose had a lower life expectancy than those on a fructose-free diet. These results suggest that, like in humans, fructose has a negative effect on worm survival, which makes them an easy, attractive model to study the effects of fructose on health.

Nonalcoholic Fatty Liver Disease (NAFLD) is a condition where a surplus of triglycerides or fat are present in the liver. In this study, ezetimibe, a cholesterol lowering drug, was used to treat flies modeling NAFLD. Compared to the coconut oil fed flies that were transferred to the control medium, the flies transferred to the control medium treated with ezetimibe showed a decrease in their triglyceride and alanine transaminase level.

Chlorella sp. are unicellular green algae that use photosynthesis to reduce carbon dioxide into glucose. In this study, authors sought to determine the temperature that Chlorella sp. is maximally efficient at photosynthesis, and therefore removing the most carbon dioxide from the system. This activity could be harnessed to naturally remove carbon dioxide from the environment, fighting the effects of climate change.

Alzheimer’s disease (AD) is a type of dementia that affects more than 5.5 million Americans, and there are no approved treatments that can delay the advancement of the disease. In this work, Xu and Mitchell test the effects of various herbal extracts (bugleweed, hops, sassafras, and white camphor) on Aβ_1-40 peptide levels in human neuroblastoma cells. Their results suggest that bugleweed may have the potential to reduce Aβ_1-40 levels through its anti-inflammatory properties.

Acquired immunodeficiency syndrome (AIDS) is a life-threatening condition caused by the human immunodeficiency virus (HIV). In this work, Takemaru et al explored the role of Coiled-Coil Domain-Containing 11 (CCDC11) in HIV-1 budding. Their results suggest that CCDC11 is critical for efficient HIV-1 budding, potentially indicating CCDC11 a viable target for antiviral therapeutics without major side effects.