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In this study, we aimed to characterize CD44-mediated regulation of the Wnt/β-catenin signaling pathway, which promotes cancer invasion and metastasis. We hypothesized that CD44 down-regulation will inhibit gastric cancer cell migration and invasion by leading to down-regulation of Wnt/β-catenin signaling. We found that CD44 up-regulation was significantly related to poor prognosis in gastric cancer patients. We demonstrated the CD44 down-regulation decreased β-catenin protein expression level. Our results suggest that CD44 down-regulation inhibits cell migration and invasion by down-regulating β-catenin expression level.

In this study, the authors investigate whether the addition of microbes from native soil enhanced the seed germination and growth of mung beans, pumpkins, and pea flower plants.

This study used single-cell RNA sequencing to examine whether B cells can predict response to pembrolizumab and radiation therapy in patients with triple-negative breast cancer.

Using a convolution neural network, these authors show machine learning can clinically diagnose breast cancer with high accuracy.

In this study, the authors investigate the effects that microplastics (which pollute fresh and saltwater ecosystems) have on plankton species Daphnia Magna by measuring their movement and viability.

In this study, the authors investigate the combinatorial effects of CO₂ plus other environmental factors including salinity, temperature, acidity, and drought on how effectively plants can transport water and carbon through their stomata.

In a world where water shortage is becoming an increasing concern, and where population increase seems inevitable, food shortage is an overwhelming concern for many. In this paper, the authors aim to characterize a drought-resistant strain of A. thaliana, investigating the cause for its water resistance. These and similar studies help us learn how plants could be engineered to improve their ability to flourish in a changing climate.

PVC is a widely used plastic that poses harmful health hazards when burned. In this study, the authors ask whether or not burned PVC (PVC char) affects bacterial transformation.

This study assesses the capacity for milkweed species, an important host plant for Monarch butterflies, to grow in desert environments with different water levels.

Habitat loss and global warming remain present-day issues that continue to place pressures on various ecosystems and their species. The authors of this paper performed studies over two years to understand whether birds feed more from wooded or exposed areas.