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Modular mimics of neuroactive alkaloids - design, synthesis, and cholinesterase inhibitory activity of rivastigmine analogs

Yu et al. | Sep 12, 2022

Modular mimics of neuroactive alkaloids - design, synthesis, and cholinesterase inhibitory activity of rivastigmine analogs

Naturally occurring neuroactive alkaloids are often studied for their potential to treat Neurological diseases. This team of students study Rivastigmine, a potent cholinesterase inhibitor that is a synthetic analog of physostigmine, which comes from the Calabar bean plant Physostigma venenosum. By comparing the effects of optimized synthetic analogs to the naturally occurring alkaloid, they determine the most favorable analog for inhibition of acetylcholinesterase (AChE), the enzyme that breaks down the neurotransmitter acetylcholine (ACh) to terminate neuronal transmission and signaling between synapses.

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Impact of Soil Productivity on the Growth of Two Meyer Lemon Trees

Shen et al. | Dec 14, 2020

Impact of Soil Productivity on the Growth of Two Meyer Lemon Trees

Here, the authors aimed to apply home soil testing to identify the cause of the growth differences between two lemon trees. They hypothesized that differences in physical and chemical soil characteristics were influencing differences in soil productivity and plant growth. Overall, the study demonstrated the effectiveness of home soil testing to characterize soils and help homeowners solve common gardening problems.

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A study to determine the anti-cancer and pro-apoptotic properties of Amaranthus spinosus Linn. Extract, AS20

Sharma et al. | Nov 24, 2020

A study to determine the anti-cancer and pro-apoptotic properties of Amaranthus spinosus Linn. Extract, AS20

In this study, the authors investigate whether a new compound has anti-cancer properties. Using the crude extract from the Amaranthus spinosus plant, HeLa cancer cells were assessed for cell death. Findings reveal that the extract (AS20) has cytotoxic effects on HeLa cells. Their findings introduce a new compound to potentially pursue in the hunt for novel cancer treatments.

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The Effects of Barley Straw (Hordeum vulgare) Extract and Barley Straw Pellets on Algal Growth and Water Quality

McHargue et al. | Oct 06, 2020

The Effects of Barley Straw (Hordeum vulgare) Extract and Barley Straw Pellets on Algal Growth and Water Quality

Algal overgrowth often threatens to clog irrigation pipes and drinking water lines when left unchecked, as well as releasing possible toxins that threaten plant and human health. It is thus important to find natural, non-harmful agents that can decrease algal growth without threatening the health of plants and humans. In this paper, the authors test the efficacy of barely extract in either liquid or pellet form in decreasing algal growth. While their results were inconclusive, the experimental set-up allows them to investigate a wider range of agents as anti-algal treatments that could potentially be adopted on a wider scale.

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Presoaking Seeds with Vinegar Improves Seed Development and Drought Tolerance in Maize Plants

D'Agate et al. | Jul 24, 2020

Presoaking Seeds with Vinegar Improves Seed Development and Drought Tolerance in Maize Plants

Climate change has contributed to the increasing annual temperatures around the world and poses a grave threat to Maize crops. Two methods proven to help combat plant drought stress effects are presoaking seeds (seeds are soaked in a liquid before planting) and the application of Acetic Acid (vinegar) to soil. The purpose of this experiment was to explore if combining these two methods by presoaking seeds with a vinegar solution can improve the seed development and plant drought tolerance of Maize plants during drought conditions.

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Creating a Phenology Trail Around Central Park Pond

Flynn et al. | Jul 16, 2020

Creating a Phenology Trail Around Central Park Pond

This study aimed to determine whether the life cycle stages, or phenophases, of some plants in the urban environment of Central Park, New York, differ from the typical phenophases of the same plant species. The authors hypothesized that the phenophases of the thirteen plants we studied would differ from their typical phenophases due to the urban heat island effect. Although the phenophases of five plants matched up with typical trends, there were distinct changes in the phenophases of the other eight, possibly resulting from the urban heat island effect.

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A Scientific Investigation of Alternative Growing Methods to Cultivate Lactuca sativa

Fishback et al. | Apr 23, 2020

A Scientific Investigation of Alternative Growing Methods to Cultivate Lactuca sativa

In this article, the authors compare different resource-efficient farming methods for the vegetable Lactuca sativa. They compared hydroponics (solid growth medium with added nutrients) to aquaponics (water with fish waste to provide nutrients) and determined efficacy by measuring plant height over time. While both systems supported plant growth, the authors concluded that aquaponics was the superior method for supporting Lactuca sativa growth. These findings are of great relevance as we continue to find the most sustainable and efficient means for farming.

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Bacterial Richness of Soil Samples from Southern New Hampshire

Chalasani et al. | Sep 21, 2016

Bacterial Richness of Soil Samples from Southern New Hampshire

Advancement in DNA sequencing technology has greatly increased our understanding about the role of bacteria in soil. The authors of this study examine the microbial content of soil samples taken from three locations in southern New Hampshire with varying pH and plant composition.

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