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Testing Various Synthetic and Natural Fiber Materials for Soundproofing

Karuppiah et al. | Jun 15, 2017

Testing Various Synthetic and Natural Fiber Materials for Soundproofing

Noise pollution negatively impacts the health and behavioral routines of humans and other animals, but the production of synthetic sound-absorbing materials contributes to harmful gas emissions into the atmosphere. The authors of this paper investigated the effectiveness of environmentally-friendly, cheap natural-fiber materials, such as jute, as replacements for synthetic materials, such as gypsum and foam, in soundproofing.

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A comparative study on the suitability of virtual labs for school chemistry experiments

Praveen et al. | Aug 22, 2022

A comparative study on the suitability of virtual labs for school chemistry experiments

Virtual labs have been gaining popularity over the last few years, especially during the worldwide lockdown due to the COVID-19 pandemic. In this study, the suitability of virtual labs for school chemistry experiments is addressed and their effectiveness is compared to traditional physical lab experiments by focusing on physical and human resources, convenience, cost, safety, and time involved as well as topic "matter".

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A novel approach for early detection of Alzheimer’s disease using deep neural networks with magnetic resonance imaging

Ganesh et al. | Mar 20, 2022

A novel approach for early detection of Alzheimer’s disease using deep neural networks with magnetic resonance imaging

In the battle against Alzheimer's disease, early detection is critical to mitigating symptoms in patients. Here, the authors use a collection of MRI scans, layering with deep learning computer modeling, to investigate early stages of AD which can be hard to catch by human eye. Their model is successful, able to outperform previous models, and detected regions of interest in the brain for further consideration.

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Toxicity of aminomethylphosphonic acid via the Wnt signaling pathway as a novel mechanism

Zhuang et al. | Mar 08, 2023

Toxicity of aminomethylphosphonic acid via the Wnt signaling pathway as a novel mechanism
Image credit: Image credit: Dapur Melodi

The Wnt signaling pathway, known to coordinate important aspects of cellular homeostasis ranging from differentiation, proliferation, migration, and much more, is dysregulated in many human diseases. This study demonstrates that aminomethylphosphonic acid, which is the main metabolite found in the common herbicide Glyphosate, is toxic to planaria and capable of binding to canonical Wnt proteins.

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The Effect of Neem on Common Nosocomial Infection-Causing Organisms

Shah et al. | Jan 27, 2020

The Effect of Neem on Common Nosocomial Infection-Causing Organisms

Nosocomial infections acquired in hospitals pose a risk to patients, a risk compounded by resistant microorganisms. To combat this problem, researchers have turned to bioactive compounds from medicinal plants such as the widely used neem. In the present study, researchers sought to determine the effectiveness of different neem preparations against several hospital acquired human pathogens. Neem powder in water successfully inhibited microorganism growth making it a potential agent to combat these infections.

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Are Age and Sex Related to Emotion Recognition Ability in Children and Teenagers?

Gallego-García et al. | Feb 23, 2018

Are Age and Sex Related to Emotion Recognition Ability in Children and Teenagers?

Humans have a natural ability to recognize emotional cues from the facial expressions of others, as a crucial evolutionary trait to navigate social interactions. This ability likely develops through normal development and social experience, but it is unclear how much influence age and sex have in emotional facial recognition (EFR). In this study, the authors investigate EFR in children and teenagers, and look at whether accurate emotional recognition does occur more in males or females.

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How Ethanol Concentration Affects Catalase Catalysis of Hydrogen Peroxide

Liu et al. | Nov 15, 2021

How Ethanol Concentration Affects Catalase Catalysis of Hydrogen Peroxide

Catalase is a critical enzyme in the human body because it is capable of converting potentially dangerous hydrogen peroxide into water and oxygen. This work asks whether ethanol affects catalase activity, as alcohol consumption has been often linked to hepatitis occurring in the liver, where catalase level is especially high, and ethanol is known to be capable of denaturing proteins. Testing different concentrations of ethanol found that higher concentrations reduced the activity of catalase. This work has important implications on the negative effects of ethanol on metabolism, in which catalase plays an important role, and protein function more broadly.

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Predicting asthma-related emergency department visits and hospitalizations with machine learning techniques

Chatterjee et al. | Oct 25, 2021

Predicting asthma-related emergency department visits and hospitalizations with machine learning techniques

Seeking to investigate the effects of ambient pollutants on human respiratory health, here the authors used machine learning to examine asthma in Lost Angeles County, an area with substantial pollution. By using machine learning models and classification techniques, the authors identified that nitrogen dioxide and ozone levels were significantly correlated with asthma hospitalizations. Based on an identified seasonal surge in asthma hospitalizations, the authors suggest future directions to improve machine learning modeling to investigate these relationships.

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Reactivity-informed design, synthesis, and Michael addition kinetics of C-ring andrographolide analogs

Zhou et al. | Nov 17, 2022

Reactivity-informed design, synthesis, and Michael addition kinetics of C-ring andrographolide analogs

Here, based on the identification of androgapholide as a potential therapeutic treatment against cancer, Alzheimer's disease, diabetes, and multiple sclerosis, due to its ability to inhibit a signaling pathway in immune system function, the authors sought ways to optimize the natural product human systems by manipulating its chemical structure. Through the semisynthesis of a natural product along with computational studies, the authors developed an understanding of the kinetic mechanisms of andrographolide and semisynthetic analogs in the context of Michael additions.

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Comparing the Dietary Preference of Caenorhabditis elegans for Bacterial Probiotics vs. Escherichia coli.

Lulla et al. | Dec 18, 2020

Comparing the Dietary Preference of <i>Caenorhabditis elegans</i> for Bacterial Probiotics vs. <i>Escherichia coli</i>.

In this experiment, the authors used C. elegans as a simple model organism to observe the impact of probiotics on the human digestive system. The results of the experiments showed that the C. elegans were, on average, most present in Chobani cultures over other tested yogurts. While not statistically significant, these results still demonstrated that C. elegans might prefer Chobani cultures over other probiotic yogurts, which may also indicate greater gut benefits from Chobani over the other yogurt brands tested.

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