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Phospholipase A2 increases the sensitivity of doxorubicin induced cell death in 3D breast cancer cell models

Lee et al. | Mar 30, 2022

Phospholipase A2 increases the sensitivity of doxorubicin induced cell death in 3D breast cancer cell models

Inefficient penetration of cancer drugs into the interior of the three-dimensional (3D) tumor tissue limits drugs' delivery. The authors hypothesized that the addition of phospholipase A2 (PLA2) would increase the permeability of the drug doxorubicin for efficient drug penetration. They found that 1 mM PLA2 had the highest permeability. Increased efficiency in drug delivery would allow lower concentrations of drugs to be used, minimizing damage to normal cells.

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Public Perception of the Effects of Artificial Sweeteners on Diabetes Based on YouTube Comments

Kim et al. | Jun 25, 2024

Public Perception of the Effects of Artificial Sweeteners on Diabetes Based on YouTube Comments
Image credit: The authors

Artificial sweeteners are rising in popularity, in part due to the influence of social media platforms like YouTube. However, YouTube commenters often repeat information about artificial sweeteners that is not supported by scientific research. To investigate how misinformation about sweeteners spreads through social media, Kim and Yoo conduct a content analysis of YouTube comments to reveal how many comments repeat misinformation about artificial sweeteners' effects.

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The Prevalence of Brain-Eating Roundworm Baylisascaris procyonis in Merrick County, Nebraska

Reeves et al. | Sep 20, 2018

The Prevalence of Brain-Eating Roundworm <i>Baylisascaris procyonis</i> in Merrick County, Nebraska

The authors investigated an important parasite-host relationship between the raccoon roundworm and the raccoon to understand how parasite prevalence is affected by location. They found that the parasite infection was more prevalent in raccoons found closer to human dwellings, though the number of roundworm eggs was not significantly different. These results are important human health, since roundworm infection is lethal to humans and can be transmitted from raccoons to humans - the authors suggest that more research into this parasite and awareness of its prevalence is needed to prevent disease.

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