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Pollination Patterns by Green-Backed Firecrown Hummingbirds

Freeland et al. | May 28, 2020

Pollination Patterns by Green-Backed Firecrown Hummingbirds

The Green-backed Firecrown hummingbird is an essential pollinator in the temperate rainforests of southern South America. However, little is known about the ecology of these birds. Authors examined the foraging patterns of these birds identifying interesting differences in foraging patterns among season, age and sex.

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Zinc-related Treatments Combined with Chloroquine and Gemcitabine for Treating Pancreatic Cancer

Ma et al. | Sep 11, 2021

Zinc-related Treatments Combined with Chloroquine and Gemcitabine for Treating Pancreatic Cancer

Pancreatic cancer is one of the deadliest cancers, with a 10% 5-year survival rate. The authors studied various dosages of TPEN and zinc in combination with Chloroquine and Gemcitabine as treatments to reduce cell proliferation. Results showed that when combined with Chloroquine and Gemcitabine, zinc and TPEN both significantly lowered cell proliferation compared to Gemcitabine, suggesting a synergistic effect that resulted in a more cytotoxic treatment. Further research and clinical trials on this topic are needed to determine whether this could be a viable treatment for pancreatic cancer.

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The Protective Antioxidant Effects of Sulforaphane on Germinating Radish Seeds Treated with Hydrogen Peroxide

Dasuri et al. | Feb 19, 2021

The Protective Antioxidant Effects of Sulforaphane on Germinating Radish Seeds Treated with Hydrogen Peroxide

Free radical chain reactions result when atoms containing unpaired electrons bind with biomolecules and alter their biological functions, contributing to the progression of diseases such as atherosclerosis, cancer, and diabetes. Antioxidants, such as vitamin E and sulforaphane, are effective neutralizers of free radicals and prevent cellular damage. This present study is conducted to determine the relative effectiveness of sulforaphane against free radicals generated by hydrogen peroxide (H2O2) compared with the known antioxidant vitamin E.

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Development of a Novel Treatment Strategy to Treat Parkinsonian Neurodegeneration by Targeting Both Lewy Body Aggregation and Dopaminergic Neuronal Degradation in a Drosophila melanogaster Model

Sama et al. | Sep 25, 2019

Development of a Novel Treatment Strategy to Treat Parkinsonian Neurodegeneration by Targeting Both Lewy Body Aggregation and Dopaminergic Neuronal Degradation in a <em>Drosophila melanogaster</em> Model

In this article the authors address the complex and life quality-diminishing neurodegenerative disease known as Parkinson's. Although genetic and/or environmental factors contribute to the etiology of the disease, the diagnostic symptoms are the same. By genetically modifying fruit flies to exhibit symptoms of Parkinson's disease, they investigate whether drugs that inhibit mitochondrial calcium uptake or activate the lysosomal degradation of proteins could improve the symptoms of Parkinson's these flies exhibit. The authors report the most promising outcome to be that when both types of drugs were used together. Their data provides encouraging evidence to support further investigation of the utility of such drugs in the treatment of human Parkinson's patients.

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Efficacy of Mass Spectrometry Versus 1H Nuclear Magnetic Resonance With Respect to Denaturant Dependent Hydrogen-Deuterium Exchange in Protein Studies

Chenna et al. | Jan 22, 2020

Efficacy of Mass Spectrometry Versus 1H Nuclear Magnetic Resonance With Respect to Denaturant Dependent Hydrogen-Deuterium Exchange in Protein Studies

The misfolding of proteins leads to numerous diseases including Akzheimer’s, Parkinson’s and Type II Diabetes. Understanding of exactly how proteins fold is crucial for many medical advancements. Chenna and Englander addressed this problem by measuring the rate of hydrogen-deuterium exchange within proteins exposed to deuterium oxide in order to further elucidate the process of protein folding. Here, mass spectrometry was used to measure exchange in Cytochrome c and was compared to archived 1H NMR data.

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The effect of wild orange essential oil on ascorbic acid decay in freshly squeezed orange juice

Sebek et al. | Feb 25, 2022

The effect of wild orange essential oil on ascorbic acid  decay in freshly squeezed orange juice

The goal of this project was to see if the addition of wild orange essential oil to freshly squeezed orange juice would help to slow down the decay of ascorbic acid when exposed to various temperatures, allowing vital nutrients to be maintained and providing a natural alternative to the chemical additives in use in industry today. The authors hypothesized that the addition of wild orange essential oil to freshly squeezed orange juice would slow down the rate of oxidation when exposed to various temperatures, reducing ascorbic acid decay. On average, wild orange EO slowed down ascorbic acid decay in freshly squeezed orange juice by 15% at the three highest temperatures tested.

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The Effect of Concentration on the Pressure of a Sodium Chloride Solution Inside Dialysis Tubing

Dye et al. | Nov 13, 2018

The Effect of Concentration on the Pressure of a Sodium Chloride Solution Inside Dialysis Tubing

In this study, the authors investigate the effects of sodium levels on blood pressure, one of the most common medical problems worldwide. They used a simulated blood vessel constructed from dialysis tubing to carefully analyze pressure changes resulting from various levels of sodium in the external solution. They found that when the sodium concentration in the simulated blood vessel was higher than the external fluid, internal pressure increased, while the reverse was true when the sodium concentration was lower than in the surrounding environment. These results highlight the potential for sodium concentration to have a significant effect on blood pressure in humans by affecting the rate of osmosis across the boundaries of actual blood vessels.

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