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Alloferon improves the growth performance and developmental time of mealworms (Tenebrio molitor)

Shon et al. | Oct 20, 2023

Alloferon improves the growth performance and developmental time of mealworms <em>(Tenebrio molitor)</em>

Mealworms (Tenebrio molitor) are important food sources for reptiles, birds, and other organisms, as well as for humans. However, the slow growth and low survival rate of mealworms cause problems for mass production. Since alloferon, a synthetic peptide, showed long-term immunological effects on mealworms, we hypothesized that alloferon would function as a growth promoter to maximize mealworm production. We discovered that the overall weight of the alloferon-containing gelatin diet group was 39.5-90% heavier, and the development time of the experimental group was shortened up to 20.6-39.6% than the control group.

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Astragalus membranaceus Root Concentration and Exposure Time: Role in Heat Stress Diminution in C. elegans

Chen et al. | Oct 17, 2018

Astragalus membranaceus Root Concentration and Exposure Time: Role in Heat Stress Diminution in <em>C. elegans</em>

In this study, the authors investigated the biological mechanism underlying the actions of a traditional medicinal plant, Astragalus membranaceus. Using C. elegans as an experimental model, they tested the effects of AM root on heat stress responses. Their results suggest that AM root extract may enhance the activity of endogenous pathways that mediate cellular responses to heat stress.

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The effect of neuroinflammation and oxidative stress on the recovery time of seizures

Kantipudi et al. | Jul 31, 2023

The effect of neuroinflammation and oxidative stress on the recovery time of seizures

Neuroinflammation and oxidative stress are both known to play a role in the occurrence and severity of seizures. This study tested effects of oxidative stress from seizures by evaluating the longevity, egg-laying, and electroshock resilience of C. elegans. Results revealed that oxidative stress and neuroinflammation diminish longevity and reproductivity while also increasing recovery time after seizures in C. elegans. This research can help lead to future studies and may also lead to finding new therapeutics for epilepsy.

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Effect of Fertilizer on Water Quality of Creeks over Time

Chen et al. | May 02, 2021

Effect of Fertilizer on Water Quality of Creeks over Time

Fertilizers are commonly used to improve agricultural yield. Unfortunately, chemical fertilizers can seep into drinking water, potentially harming humans and other forms of life. Here, the authors investigate the effect of fertilizer on the water quality of Saratoga Creek over time. They find that fertilizers can alter the acidity of the creek's water, which can be harmful to aquatic species, as well as increase the levels of nitrates temporarily.

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The gender gap in STEM at top U.S. Universities: change over time and relationship with ranking

Kruus et al. | Jun 25, 2024

The gender gap in STEM at top U.S. Universities: change over time and relationship with ranking

Authors address the gender disparity in STEM fields, examining changes in gender diversity across male-dominated undergraduate programs over 19 years at 24 top universities. Analyzing data from NCES IPEDS, it identifies STEM as persistently male-dominated but notes increasing gender diversity in many disciplines, particularly in recent years. Results indicate that higher-ranked universities in disciplines like computer science and mechanical engineering show a weak correlation with improved gender diversity, suggesting effective initiatives can mitigate the gender gap in STEM, despite ongoing challenges.

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A study of Syrian students' migration motivations, destinations, and return intentions in a time of crisis

Merjaneh et al. | Apr 16, 2026

A study of Syrian students' migration motivations, destinations, and return intentions in a time of crisis
Image credit: Aaron Burden, 2017

This study investigates the migration intentions of Syrian high school and university students amid ongoing conflict and economic instability. Drawing on survey data, the research examines how academic stage influences migration motivations, preferred destinations, and return intentions. The findings reveal a widespread desire to emigrate, driven by educational, economic, and security concerns, highlighting significant implications for Syria’s future workforce and post-conflict recovery.

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Comparative singlet oxygen photosensitizer efficiency of berberine, rose bengal, and methylene blue by time course nuclear magnetic resonance (NMR) monitoring of a photochemical 4+2 cycloaddition endoperoxide formation

Su et al. | May 14, 2021

Comparative singlet oxygen photosensitizer efficiency of berberine, rose bengal, and methylene blue by time course nuclear magnetic resonance (NMR) monitoring of a photochemical 4+2 cycloaddition endoperoxide formation

Berberine, a natural product alkaloid, has been shown to exert biological activity via in situ production of singlet oxygen when photo irradiated. Berberine utilizes singlet oxygen in its putative mechanism of action, wherein it forms an activated complex with DNA and photosensitizes triplet oxygen to singlet oxygen to specifically oxidize guanine residues, thereby halting cell replication and leading to cell death. This has potential application in photodynamic therapy, alongside other such compounds which also act as photosensitizers and produce singlet oxygen in situ. The quantification of singlet oxygen in various photosensitizers, including berberine, is essential for determining their photosensitizer efficiencies. We postulated that the singlet oxygen produced by photoirradiation of berberine would be superior in terms of singlet oxygen production to the aforementioned photosensitizers when irradiated with UV light, but inferior under visible light conditions, due to its strong absorbance of UV wavelengths.

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