Browse Articles

In this study, Imani et al. investigate whether a new proprietary herbal formulation, HF1, can inhibit expression of immune suppressor protein PD-L1. PD-L1 is a transmembrane protein that can be expressed by cancer cells to assist in their ability to avoid attacks from the immune system. Work from this study demonstrates that HF1 treatment can reduce expression of PD-L1 in cultured cancer cells, implicating HF1 as a potential new cancer therapy.

In this study, we aimed to characterize CD44-mediated regulation of the Wnt/β-catenin signaling pathway, which promotes cancer invasion and metastasis. We hypothesized that CD44 down-regulation will inhibit gastric cancer cell migration and invasion by leading to down-regulation of Wnt/β-catenin signaling. We found that CD44 up-regulation was significantly related to poor prognosis in gastric cancer patients. We demonstrated the CD44 down-regulation decreased β-catenin protein expression level. Our results suggest that CD44 down-regulation inhibits cell migration and invasion by down-regulating β-catenin expression level.

In this study, the authors investigate whether the addition of microbes from native soil enhanced the seed germination and growth of mung beans, pumpkins, and pea flower plants.

Using a convolution neural network, these authors show machine learning can clinically diagnose breast cancer with high accuracy.

In this study, the authors investigate the effects that microplastics (which pollute fresh and saltwater ecosystems) have on plankton species Daphnia Magna by measuring their movement and viability.

In this study, the authors investigate the combinatorial effects of CO₂ plus other environmental factors including salinity, temperature, acidity, and drought on how effectively plants can transport water and carbon through their stomata.

In a world where water shortage is becoming an increasing concern, and where population increase seems inevitable, food shortage is an overwhelming concern for many. In this paper, the authors aim to characterize a drought-resistant strain of A. thaliana, investigating the cause for its water resistance. These and similar studies help us learn how plants could be engineered to improve their ability to flourish in a changing climate.

PVC is a widely used plastic that poses harmful health hazards when burned. In this study, the authors ask whether or not burned PVC (PVC char) affects bacterial transformation.

This study analyzes genetic alterations and expression patterns of protein kinases involved in phagocytosis across multiple cancers using TCGA data.

The authors looked at the impact of citrate and lactate on glioblastoma progression. Their results provide important insights for future immunotherapies aimed at treating glioblastoma.