Evidence suggests certain food preservatives may be genotoxic due to their ability to impair normal cellular pathways. The authors investigated the genotoxic potential and effects of commonly used synthetic food preservatives, specifically sodium nitrite, potassium sulfate, and hydrogen peroxide.
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Capturing Harmful Air Pollutants Using an Electrospun Mesh Embedded with Zinc-based Nanocrystals
Zeolithic imidazolate framework-8 (ZIF-8) is a specific metal-organic framework that has favorable qualities for use in an air filter and is known to be capable of adsorbing particulate matter. Therefore, the objective of this experiment was to determine the effectiveness of ZIF-8 in adsorbing polar, gaseous air pollutants, specifically nitrogen dioxide and hydrogen sulfide. In order to determine effectiveness, the percent change in concentration for various gases after the application of ZIF-8 crystals was measured via Fourier-transform infrared spectroscopy (FTIR). The work highlights crystals as a potentially promising alternative or addition to current filter materials to reduce atmospheric pollution.
Read More...Photometric analysis of Type Ia Supernova 2023jvj
Here the authors conducted a photometric analysis of Supernova (SN) 20234jvj. Through generating a light curve, they determined SN 2023jvj to be a Type Ia supernova located approximately 1.246e8 parasecs away from Earth.
Read More...Converting SiO2 wafers to hydrophobic using chlorotrimethylsilane
Semiconductors are the center of the fourth industrial revolution as they are key components for all electronics. Exposed wafers made of silicon (Si), which can easily oxidize, convert to silicon dioxide (SiO2). The surface of SiO2 wafers consists of many Si-OH bonds, allowing them to easily bond with water, resulting in a “wet” or hydrophilic condition. We sought to determine a way to modify the surface of SiO2 wafers to become hydrophobic to ensure safe wet cleaning.
Read More...The effects of plasticizers on the mechanical properties and chemical composition of a gelatin biopolymer
Here, in an effort to identify alternatives to oil-based plastic, the authors sought to investigate the effects of plasticizers on the mechanical properties and chemical composition of gelatin bioplastic matrices. Through measurements of their tensile strength and elongation at break, along with FTIR spectroscopy, they identified 3% w/v polyethylene glycol film as having the best performance in their study..
Read More...Optical anisotropy of crystallized vanillin thin film: the science behind the art
Microscopic beauty is hiding in common kitchen ingredients - even vanillin flavoring can be turned into mesmerizing artwork by crystallizing the vanillin and examining it under a polarizing microscope. Wang and Pang explore this hidden beauty by determining the optimal conditions to grow crystalline vanillin films and by creating computer simulations of chemical interactions between vanillin molecules.
Read More...The design of Benzimidazole derivatives to bind to GDP-bound K-RAS for targeted cancer therapy
In this study, the authors looked at a proto-oncogene, KRAS, and searched for molecules that are predicted to be able to bind to the inactive form of KRAS. They found that a modified version of Irbesartan, a derivative of benzimidazole, showed the best binding to inactive KRAS.
Read More...Evaluating the feasibility of SMILES-based autoencoders for drug discovery
The authors investigate the ability of machine learning models to developing new drug-like molecules by learning desired chemical properties versus simply generating molecules that similar to those in the training set.
Read More...Deuterated solvent effects in the kinetics and thermodynamics of keto-enol tautomerization of ETFAA
In this study, the authors determined whether tautomerization dynamics in protic and aprotic solvents displayed differences in reaction rates and in the proportion of the keto and enol tautomers present.
Read More...Innovative Treatment for Reducing Senescence and Revitalizing Aging Cells through Gene Silencing
Cellular senescence plays a key role in aging cells and is attributed to a number of disease and pathology. These authors find that genetic editing of both RPS6KB1 and PPARGC1A revitalizes a human skin fibroblast cell line.
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