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Understanding how bacteria respond to other bacteria could facilitate their ability to initiate and maintain their infectiousness. The phenomenon by which bacteria signal to each other via chemical signals is called quorum sensing, which could be targeted to deter bacterial infection in some cases if better understood. In this article, the authors study how a bacterium called V. fischeri uses quorum sensing to change bioluminescence, an easy readout that facilitates studying quorum sensing in this strain.

Here the authors investigate the use of social media in adults with Autism Spectrum Disorder (ASD) in affecting their ability and opportunities to interact with others. They found that higher usage of Internet correlated with less severe anxiety symptoms and improved social skills.

Alzheimer’s disease (AD) is a type of dementia that affects more than 5.5 million Americans, and there are no approved treatments that can delay the advancement of the disease. In this work, Xu and Mitchell test the effects of various herbal extracts (bugleweed, hops, sassafras, and white camphor) on Aβ_1-40 peptide levels in human neuroblastoma cells. Their results suggest that bugleweed may have the potential to reduce Aβ_1-40 levels through its anti-inflammatory properties.

Here the authors strive to remedy the financial and mechanical deficiencies in current prosthetics by building a simple, noninvasive vibratory sensory feedback system into an inexpensive constructed 3D-printed prosthetic arm. They find that this simple feedback system has the potential to enhance feedback performance at a less cost.

Chronic alcohol consumption can cause cardiac myopathy, which afflicts about 500,000 Americans annually. Gunturi et al. wanted to understand the effects of alcohol on heart rate and confirm the role of nitric oxide (NO) signaling in heart rate regulation. Using the model organism Daphnia magna, a water crustacean with a large, transparent heart, they found that the heart rate of Daphnia magna was reduced after treatment with alcohol. This depression could be reversed after treatment with inhibitors of NO synthesis and signaling. Their work has important implications for how we understand alcohol-induced effects on heart rate and potential treatments to reverse heart rate depression as a result of alcohol consumption.

Alzheimer's disease is one of the leading causes of death in the United States and is characterized by neurodegeneration. Mishra et al. wanted to understand the role of two transport proteins, LRP1 and AQP4, in the neurodegeneration of Alzheimer's disease. They used a model organism for Alzheimer's disease, the nematode C. elegans, and genetic engineering to look at whether they would see a decrease in neurodegeneration if they increased the amount of these two transport proteins. They found that the best improvements were caused by increased expression of both transport proteins, with smaller improvements when just one of the proteins is overly expressed. Their work has important implications for how we understand neurodegeneration in Alzheimer's disease and what we can do to slow or prevent the progression of the disease.

While tea has a complex history, recently the health benefits of this beverage have come into focus. In this study, researchers sought to compare the levels of caffeine, catechins and L-theanine between different types of tea using NMR spectroscopy. Further, the impact of brewing temperature on the release of these compounds was also assessed. Of those tested, Bao Chong tea had the highest levels of these compounds. Brewing temperatures between 45ºC and 75ºC were found to be optimal for compound release. These results can help consumers make informed choices about their tea preparation and intake.

Previously established data indicate that cemeteries have contributed to groundwater and soil pollution, as embalming fluids can impact the microbiomes that exist in decomposing remains. In this study, Caputo et al hypothesized that microbial variation would be high between cemeteries from different eras due to dissimilarities between embalming techniques employed, and furthermore, that specific microbes would act as an indication for certain contaminants. Overall, they found that there is a variation in the microbiomes of the different eras’ cemeteries according to the concentrations of the phyla and their more specific taxa.

Music is an important part of the day for many of us, but what makes some combinations of sound more pleasant to the ear than others? In this article the authors investigate the role of some characteristics of sound on the perception of a pleasant vs harsh musical note.

With growing demands for ethanol, many researchers are turning to Panicum virgatum (switchgrass) as a feedstock of cellulosic ethanol. In this study, Ferris and Gillan examine the germination, biomass, nitrogen, survival, and chlorophyll absorbance of two switchgrass cultivars of grown in competition with Bromus inermis (smooth brome) with two varying levels of nitrogen fertilizer. Results presented indicate that during establishment, competition from other species has a greater effect than nitrogen fertilizer.