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To best identify tuberculosis and pneumonia diagnoses in chest x-rays, the authors compare different deep learning convolution neural networks.

In this study, the effects of vitamin C, ginger, or curcumin supplements on C-reactive protein levels in healthy participants are determined in an eight-week open-label trial.

In this study, with consideration for the increasing participation of high school students in indoor rowing, the authors analyzed World Indoor Rowing Championship data. Statistical analysis revealed two key features that can determine the performance of a rower as well as increasing competitiveness in nearly all categories considered. They conclude by offering a 2000-meter ergometer time distribution that can help junior rowers assess their current performance relative to the world competition.

India accounts for over 2.4 million recorded cases of tuberculosis, about 26% of the world’s cases. This research ascertained the bearing of both the population density and the average elevation above mean sea level (MSL) on the number of cases of TB recorded by the districts in Maharashtra, India. The results found a strong positive correlation between the number of TB cases per thousand people and the population density and a strong negative correlation between the number of TB cases per thousand people and the average elevation above MSL.

The diagnosis of malaria remains one of the major hurdles to eradicating the disease, especially among poorer populations. Here, the authors use machine learning to improve the accuracy of deep learning algorithms that automate the diagnosis of malaria using images of blood smears from patients, which could make diagnosis easier and faster for many.

Pancreatic ductal adenocarcinoma (PDAC) is the most common form of pancreatic cancer, with early diagnosis and treatment challenges. When any of the genes KRAS, SMAD4, TP53, and BRCA2 are heavily mutated, they correlate with PDAC progression. Cellular stress, partly regulated by the gene SERPINA6, also correlates with PDAC progression. When SERPINA6 is highly expressed, corticosteroid-binding globulin inhibits the effect of the stress hormone cortisol. In this study, the authors explored whether there is an inverse correlation between the expression of SERPINA6 and PDAC-linked genes.

This study aimed to assess the role of 25-hydroxyvitamin D3 solution, at varying concentrations, in protecting vertical transmission of diabetic-like phenotypes. We hypothesized that the highest concentration of vitamin D solution (55 ng/mL) would be most effective in having a protective role. The results indicated that the hypothesis was partially supported; overall, all three concentrations of the vitamin D solution administered to the flies reared on HSDs had a protective effect, to varying extents.

Pancreatic cancer is one of the deadliest cancers, with a 10% 5-year survival rate. The authors studied various dosages of TPEN and zinc in combination with Chloroquine and Gemcitabine as treatments to reduce cell proliferation. Results showed that when combined with Chloroquine and Gemcitabine, zinc and TPEN both significantly lowered cell proliferation compared to Gemcitabine, suggesting a synergistic effect that resulted in a more cytotoxic treatment. Further research and clinical trials on this topic are needed to determine whether this could be a viable treatment for pancreatic cancer.

Reaching one’s maximum jump height requires optimizing one’s jump techniques. In order to find this optimal jump technique, three high school participants with varying vertical jump (VJ) abilities recorded videos of themselves with varying degrees of maximum/minimum shoulder, knee, and hip angles—with or without respect to the horizontal—at the isometric phase of a regular countermovement (CM) VJ or countermovement jump (CMJ). Results showed that the shoulder angle without respect to the horizontal (SA), knee angle with respect to the horizontal (KAH), and the hip angle with respect to the horizontal (HAH) possessed a more consistent correlation with VJ height across the subjects compared to the same respective angles with opposite relations to the horizontal.

Alcohol use disorder is a chronic, relapsing disease that affects millions of Americans every day. There are limited treatment options for alcohol dependence and alcohol withdrawal symptoms, including depression and anxiety. Previous studies have shown that probiotics can decrease depression in rodents during maternal separation and anxiety in humans. Therefore, we hypothesized that the ethanol-withdrawn planaria who consumed probiotics would have decreased withdrawal symptoms as measured by increased motility compared to the ethanol-withdrawn planaria that were not fed probiotics. The ethanol-withdrawn planaria had a statistically significant decrease in motility compared to the control group, while the planaria that consumed probiotics had no statistically significant change in motility compared to the control group.