Here seeking to develop a method to diagnose, hypertrophic cardiomyopathy which can cause sudden cardiac death, the authors investigated the use of a convolutional neural network (CNN) and long short-term memory (LSTM) models to classify cardiac magnetic resonance and heart electrocardiogram scans. They found that the CNN model had a higher accuracy and precision and better other qualities, suggesting that machine learning models could be valuable tools to assist physicians in the diagnosis of hypertrophic cardiomyopathy.
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Evaluation of the causality between testosterone, obesity, and diabetes
The study explored the role of testosterone beyond its well-established effects on male sex characteristics, focusing on its association with non-communicable diseases (NCDs) like obesity and type 2 diabetes (T2D), using Mendelian randomization (MR) analysis on genomic data.
Read More...Predictions of neural control deficits in elders with subjective memory complaints and Alzheimer’s disease
The authors compare neuroimaging datasets to identify potential new biomarkers for earlier detection of Alzheimer's disease.
Read More...Influenza vaccine effectiveness by age for Influenza A/B viruses between 2011-2020
In this manuscript the authors looked at current vaccine strategies against different strains of influenza. Looking at several factors they found that influenza strain as well as vaccinated age group, among other factors, impact vaccine effectiveness.
Read More...Differences in postoperative satisfaction between orthopedic and cosmetic patients
In this study, the authors investigate differences in psychological outcomes from patients who undergo different surgical procedures.
Read More...Ramifications of natural and artificial sweeteners on the gastrointestinal system
This study aimed to determine whether artificial sweeteners are harmful to the human microbiome by investigating two different bacteria found to be advantageous to the human gut, Escherichia coli and Bacillus coagulans. Results showed dramatic reduction in bacterial growth for agar plates containing two artificial sweeteners in comparison to two natural sweeteners. This led to the conclusion that both artificial sweeteners inhibit the growth of the two bacteria and warrants further study to determine if zero-sugar sweeteners may be worse for the human gut than natural sugar itself.
Read More...Failure of colony growth in probiotic Lactobacillus casei Shirota as result of preservative sorbic acid
This study tested the proficiency of different concentrations of the antimicrobial sorbic acid to inhibit the probiotic Lactobacillus casei Shirota. It was hypothesized that sorbic acid’s use as a bacterial deterrent would also target this bacterial strain of Lactobacillus. The results supported the hypothesis, with the colony count of L. casei Shirota having significant decreases at all concentrations of sorbic acid. These results additionally suggest that even under the FDA sorbic acid restrictions of 0.03% concentration, damaging effects could be seen in L. casei Shirota.
Read More...In vitro characterization of umilical cord-dervied MSC's supplemented with PLAY®:A potential FBS substitute
FBS is an important component in in vitro cell culture work, helping to provide needed nutrients to cells to grow. The authors look at the ability of an alternative to FBS to support cell growth in culture.
Read More...Association between nonpharmacological interventions and dementia: A retrospective cohort study
Here, the authors investigated the role of nonpharmacological interventions in preventing or delaying cognitive impairment in individuals with and without dementia. By using a retrospective case-control study of 22 participants across two senior centers in San Diego, they found no significant differences in self-reported activities. However, they found that their results reflected activity rather than the activity itself, suggesting the need for an alternative type of study.
Read More...How visualization influences strength endurance
Recognizing a potential link between mental focus and physical endurance, here, the authors considered the effects of mental visualization on strength endurance. By comparing the number of repetitions completed in sets where the lifter was aware of the weight to be lifted against sets where the lifter was kept unaware, they found that the lifter was able to maintain strength endurance when unable to accurately visualize the weight they lifted in this exploratory study.
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