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Evaluating Biomarkers and Treatments for Acute Kidney Injury in a Zebrafish Model

Mathew et al. | Aug 11, 2019

Evaluating Biomarkers and Treatments for Acute Kidney Injury in a Zebrafish Model

Coronary Artery Disease (CAD) is the leading cause of death in the United States, and 81% of Acute Kidney Injury (AKI) patients in the renal fibrosis stage later develop CAD. In this study, Mathew and Joykutty aimed to create a cost-effective strategy to treat AKI and thus prevent CAD using a model of the zebrafish, Danio rerio. They first tested whether AKI is induced in Danio rerio upon exposure to environmental toxins, then evaluated nitrotyrosine as an early biomarker for toxin-induced AKI. Finally, they evaluated 4 treatments of renal fibrosis, the last stage of AKI, and found that the compound SB431542 was the most effective treatment (reduced fibrosis by 99.97%). Their approach to treating AKI patients, and potentially prevent CAD, is economically feasible for translation into the clinic in both developing and developed countries.

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The Development and Maximization of a Novel Photosynthetic Microbial Fuel Cell Using Rhodospirillum rubrum

Gomez et al. | Mar 02, 2014

The Development and Maximization of a Novel Photosynthetic Microbial Fuel Cell Using <em>Rhodospirillum rubrum</em>

Microbial fuel cells (MFCs) are bio-electrochemical systems that utilize bacteria and are promising forms of alternative energy. Similar to chemical fuel cells, MFCs employ both an anode (accepts electrons) and a cathode (donates electrons), but in these devices the live bacteria donate the electrons necessary for current. In this study, the authors assess the functionality of a photosynthetic MFC that utilizes a purple non-sulfur bacterium. The MFC prototype they constructed was found to function over a range of environmental conditions, suggesting its potential use in industrial models.

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Development of novel biodegradable bioplastics for packaging film using mango peels

Wang et al. | Apr 06, 2025

Development of novel biodegradable bioplastics for packaging film using mango peels
Image credit: JACQUELINE BRANDWAYN

Here the authors explored the development of biodegradable bioplastic films derived from mango peels as a sustainable solution to plastic pollution and greenhouse gas emissions from fruit waste. They optimized the film's mechanical properties and water resistance through adjusting processing conditions and incorporating plasticizers and a hydrophobic coating, ultimately demonstrating its potential as a bacteriostatic and biodegradable alternative to conventional plastic food wrap.

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An exploration of western mosquitofish as the animal component in an aquaponic farming system

Medina et al. | Dec 03, 2024

An exploration of western mosquitofish as the animal component in an aquaponic farming system
Image credit: The authors

Aquaponics (the combination of aquatic plant farming with fish production) is an innovative farming practice, but the fish that are typically used, like tilapia, are expensive and space-consuming to cultivate. Medina and Alvarez explore other options test if mosquitofish are a viable option in the aquaponic cultivation of herbs and microgreens.

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Polluted water tested from the Potomac River affects invasive species plant growth

Chao et al. | Sep 20, 2023

Polluted water tested from the Potomac River affects invasive species plant growth
Image credit: Alex Korolkoff

Here recognizing the potential for pollution to impact the ecosystems of local waterways, the authors investigated the growth of tiger lilies, which are invasive to the Potomac River, in relation to the level of pollution. The authors report that increasing levels of pollution led to increased growth of the invasive species based on their study.

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Investigation of the correlation between trihalomethane concentrations and socioeconomic factors in NY State

Lee et al. | Aug 19, 2023

Investigation of the correlation between trihalomethane concentrations and socioeconomic factors in NY State

Trihalomethanes, probable human carcinogens, are commonly found disinfection by-products (DBPs) in public water systems (PWS). The authors investigated the correlation between trihalomethane concentrations and socioeconomic factors in New York State, finding a negative correlation between median household income and trihalomethane concentrations. The inverse association between trihalomethanes and household income may indicate socioeconomic disparity regarding drinking water quality and the need for improved efforts to assist small- and medium-sized community water systems to lower DBP levels in New York State.

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From trash to treasure: A sustainable approach to oil spill clean-up

Kathir et al. | Aug 02, 2023

From trash to treasure: A sustainable approach to oil spill clean-up

In this study the authors looked at sustainable ways to clean up oil spills that harm marine life. Using water spangle leaves and milk week the authors looked at the ability to recovery oil from both fresh and salt water and the ability to reuse the organic material to clean up spills. Their results show promise to help find a sustainable, eco-friendly way to clean up oil spills and protect marine life and habitats.

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