The study discusses the relationship between bacterial species and the human gut microbiome, emphasizing the role of quorum sensing molecules in bacterial communication and its implications for health. Authors investigated the impact of bacterial supernatants from Escherichia coli (E. coli) on the growth of new E. coli and Enterobacter aerogenes (E. aerogenes) cultures.
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The Impact of Antibiotic Exposure and Concentration on Resistance in Bacteria
Antibiotics are used to treat dangerous diseases. Over time, however, bacteria are becoming resistant to antibiotics - which poses a threat to humans and animals alike. In this paper, the authors examine how E. coli gains resistance to the antibiotic amoxicillin.
Read More...Cocktail therapy to inhibit multispecies biofilm in cystic fibrosis patients
Here, recognizing the important role of bacterial biofilms in many life-threatening chronic infections, the authors investigated the effectiveness of a combination treatment on biofilms composed of up to three different common species within the lungs of cystic fibrosis patients with computational analysis. They found that a triple cocktail therapy targeting three different signaling pathways has significant potential as both a treatment and prophylaxis.
Read More...The effect of bioenhancers on ampicillin-sulbactam as a treatment against A. baumannii
This article explores the potential of piperine, a bioenhancer from black pepper, to improve antibiotic efficacy against antibiotic-resistant Acinetobacter baumannii. By combining piperine with ampicillin-sulbactam, the study demonstrated a significant reduction in bacterial growth for most strains tested, showcasing the promise of bioenhancers in combating resistant pathogens. This research highlights the possibility of reducing the required antibiotic dosage, potentially offering a new strategy in the fight against drug-resistant bacteria.
Read More...Analysis of ultraviolet light as a bactericide of gram-negative bacteria in Cladophora macroalgae extracts
Here, the authors sought to use Cladophora macroalgae as a possible antibiotic to address the growing threat of antibiotic resistance in pathogenic bacteria. However, when they observed algae extracts to be greatly contaminated with gram-negative bacteria, they adapted to explore the ability to use ultraviolet light as a bactericide. They found that treatment with ultraviolet light had a significant effect.
Read More...An Aqueous Solution Containing Soluble Substances From PVC Char Has No Effect on the Rate of Transformation in E. coli Cells
PVC is a widely used plastic that poses harmful health hazards when burned. In this study, the authors ask whether or not burned PVC (PVC char) affects bacterial transformation.
Read More...Phages Can Be More Effective and Specific Than Antibiotics in Combating Bacteria
Phage therapy has been suggested as an alternative to antibiotics because bacteria resistant to antibiotics may still be susceptible to phages. However, phages may have limited effectiveness in combating bacteria since bacteria possess several antiviral defense mechanisms and can quickly develop resistance to phages. In this study, Wu and Pinta compare the effectiveness and specificity of antibiotics and phages in combating bacteria. They found that T4 phages are more specific and effective in fighting or inhibiting both antibiotic-resistant and sensitive bacteria than antibiotics, suggesting that phage therapy can be developed as an efficient tool to combat antibiotic-resistant bacteria.
Read More...Strain-selective in vitro and in silico structure activity relationship (SAR) of N-acyl β-lactam broad spectrum antibiotics
In this study, the authors investigate the antibacterial efficacy of penicillin G and its analogs amoxicillin, carbenicillin, piperacillin, cloxacillin, and ampicillin, against four species of bacteria. Results showed that all six penicillin-type antibiotics inhibit Staphylococcus epidermidis, Escherichia coli, and Neisseria sicca with varying degrees of efficacy but exhibited no inhibition against Bacillus cereus. Penicillin G had the greatest broad-spectrum antibacterial activity with a high radius of inhibition against S. epidermidis, E. coli, and N. sicca.
Read More...Star anise and oregano essential oil: A comparative evaluation of antibacterial effect
The authors looked at the antibacterial effects of oregano and star anise essential oils against E. coli or S. epidermis. They found that oregano oil showed antibacterial activity against both E. coli or S. epidermis, and that star anise oil had a larger zone of inhibition in E. coli than tetracycline, a conventional antibiotic.
Read More...Myrtaceaes as antimicrobial agents against Staphylococcus aureus and Pseudomonas aeruginosa
In this study, the authors test new antimicrobials by measuring the ability of extracts from Australian-native Myrtaceae species to induce death of two bacteria S. aureus and P. aeruginosa.
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