The authors studied the impact of drying blood as a storage solution for space travel.
Read More...The effects of rocket travel and near-space environment on dried blood and blood plasma
In silico design of novel acetylcholinesterase inhibitors as potential therapeutics for Alzheimer's disease
Elevated acetylcholinesterase (AChE) activity contributes to cognitive decline and neurodegenerative diseases such as Alzheimer’s, motivating the search for more effective inhibitors with better bioavailability. This study used computational methods to design novel, non-toxic AChE inhibitors.
Read More...Protein kinases in phagocytosis (phagocytotic kinome): A promising biomarker set in cancer therapeutics
This study analyzes genetic alterations and expression patterns of protein kinases involved in phagocytosis across multiple cancers using TCGA data.
Read More...Nonthermal nitrogen fixation with air and water by using a low-pressure plasma
Glucose concentration and the longevity of cut roses: sugar-induced senescence
The authors examined the effect of varying glucose concentrations on cut rose longevity.
Read More...Initiating astrocyte to neuron transdifferentiation via miR-124a: implications in neurodegenerative disease
The authors looked at whether they could induce the formation of new neurons from astrocytes via the upregulation of a microRNA (miR-124a). They found that upregulation of miR-124a started transdifferentiation of neurons, but was not enough to lead to full conversion of astrocytes to neurons.
Read More...In silico screening of DEAB analogues as ALDH1 isoenzymes inhibitors in cancer treatment
The authors computationally screened potential ALDH1 inhibitors, for use as potential cancer therapeutics.
Read More...Simple solving heuristics improve the accuracy of sudoku difficulty classifiers
Higher pH level increases the efficacy of calcium phosphate-mediated intracellular delivery
This study investigated the impact of pH on the efficiency of calcium phosphate, used as a drug delivery agent.
Read More...Survival analysis in cardiovascular epidemiology: nexus between heart disease and mortality
In 2021, over 20 million people died from cardiovascular diseases, highlighting the need for a deeper understanding of factors influencing heart failure outcomes. This study examined multiple variables affecting mortality after heart failure, using random forest models to identify time, serum creatinine, and ejection fraction as key predictors. These findings could contribute to personalized medicine, improving survival rates by tailoring treatment strategies for heart failure patients.
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