Naturally occurring neuroactive alkaloids are often studied for their potential to treat Neurological diseases. This team of students study Rivastigmine, a potent cholinesterase inhibitor that is a synthetic analog of physostigmine, which comes from the Calabar bean plant Physostigma venenosum. By comparing the effects of optimized synthetic analogs to the naturally occurring alkaloid, they determine the most favorable analog for inhibition of acetylcholinesterase (AChE), the enzyme that breaks down the neurotransmitter acetylcholine (ACh) to terminate neuronal transmission and signaling between synapses.
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An analysis of junior rower performance and how it is affected by rower's features
In this study, with consideration for the increasing participation of high school students in indoor rowing, the authors analyzed World Indoor Rowing Championship data. Statistical analysis revealed two key features that can determine the performance of a rower as well as increasing competitiveness in nearly all categories considered. They conclude by offering a 2000-meter ergometer time distribution that can help junior rowers assess their current performance relative to the world competition.
Read More...Propagation of representation bias in machine learning
Using facial recognition as a use-case scenario, we attempt to identify sources of bias in a model developed using transfer learning. To achieve this task, we developed a model based on a pre-trained facial recognition model, and scrutinized the accuracy of the model’s image classification against factors such as age, gender, and race to observe whether or not the model performed better on some demographic groups than others. By identifying the bias and finding potential sources of bias, his work contributes a unique technical perspective from the view of a small scale developer to emerging discussions of accountability and transparency in AI.
Read More...The effect of floating plant on water purification: Comparison of the water purification capability of Water Hyacinth, Duckweed, and Azolla
Clean water is a necessity for every household, yet water pollution is a serious problem in many parts of the world and plays a major role in compromising water security in the 21st century. In this paper, the authors address the utility of several plants as natural water purifiers. They estimate the effectiveness of duckweed, hyacinth, and azolla in improving the quality of water from the Mithi river in India by measuring several metrics. They conclude that all three plants are effective in improving water quality, suggesting that these plants as eco-friendly options for water treatment.
Read More...Characterization of Drought Tolerance in Arabidopsis Mutant fry1-6
In a world where water shortage is becoming an increasing concern, and where population increase seems inevitable, food shortage is an overwhelming concern for many. In this paper, the authors aim to characterize a drought-resistant strain of A. thaliana, investigating the cause for its water resistance. These and similar studies help us learn how plants could be engineered to improve their ability to flourish in a changing climate.
Read More...Differentiation of Waste Plastic Pyrolysis Fuels to Conventional Diesel Fuel
Plastic pollution and energy shortages are pressing issues in today’s world. The authors examined whether waste plastic pyrolysis fuels are similar to conventional diesel and, thus, a plausible alternative fuel. Results showed that waste plastic pyrolysis fuels did not match up to diesel overall, though several fuels came close in calorific value.
Read More...The Effect of Sunglass Price on Ocular Exposure to Ultraviolet Radiation
Wearing sunglasses may offer protection against the negative health outcomes linked to exposure to ultraviolet waves. In this study, the authors test whether more expensive sunglasses offer better UV protection.
Read More...The Effect of Positive and Negative Reinforcement on Sixth Graders’ Mental Math Performance
What type of motivation is more effective: reward or punishment? In this study, the authors assess the effects of positive or negative on the math scores of sixth graders.
Read More...Antibacterial activity of homemade Indian tomato tamarind soup (rasam) against common pathogens
Systematic consumption of traditional foods is a popular way of treating diseases in India. Rasam, a soup of spices and tomato with a tamarind base, is a home remedy for viral infections such as the common cold. Here, we investigate if rasam, prepared under household conditions, exhibits antibacterial activity against Escherichia coli and Staphylococcus aureus, two common pathogenic bacteria. Our results show rasam prepared under household conditions lacks antibacterial activity despite its ingredients possessing such properties.
Read More...Epileptic seizure detection using machine learning on electroencephalogram data
The authors use machine learning and electroencephalogram data to propose a method for improving epilepsy diagnosis.
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