Human cytomegalovirus (HCMV) causes serious infections in immunocompromised patients and therapies to inhibit latent HCMV are not developed. Using CRISPR/Cas9, the authors were able to delete an important promoter region in HCMV.
Read More...Using CRISPR technology to inhibit the replication of human cytomegalovirus by deletion of a gene promoter
Human cytomegalovirus (HCMV) causes serious infections in immunocompromised patients and therapies to inhibit latent HCMV are not developed. Using CRISPR/Cas9, the authors were able to delete an important promoter region in HCMV.
Read More...Manipulation of extracellular matrix mechanical cues to stimulate oligodendrocytes to promote remyelination
Oligodendrocytes are specialized brain cells that can change to cells that produce myelin and protect nerves. This study investigates the capacity for different extracellular matrix cues to induce this effect in culture.
Read More...The Development and Maximization of a Novel Photosynthetic Microbial Fuel Cell Using Rhodospirillum rubrum
Microbial fuel cells (MFCs) are bio-electrochemical systems that utilize bacteria and are promising forms of alternative energy. Similar to chemical fuel cells, MFCs employ both an anode (accepts electrons) and a cathode (donates electrons), but in these devices the live bacteria donate the electrons necessary for current. In this study, the authors assess the functionality of a photosynthetic MFC that utilizes a purple non-sulfur bacterium. The MFC prototype they constructed was found to function over a range of environmental conditions, suggesting its potential use in industrial models.
Read More...Design and implementation of a cryptographically secure electronic voting infrastructure
In this study, the authors present proposed cryptographic controls for election sites with the hypothesis that this will mitigate risk and remediate vulnerabilities.
Read More...The effect of viscous drag on damped simple harmonic motion
Dynamic viscosity is a quantity that describes the magnitude of a fluid’s internal friction or thickness. Traditionally, scientists measure this quantity by either calculating the terminal velocity of a falling sphere or the time a liquid takes to flow through a capillary tube. However, they have yet to conduct much research on finding this quantity through viscous damped simple harmonic motion. The present study hypothesized that the relationship between the dynamic viscosity and the damping coefficient is positively correlated.
Read More...Developing a Portable, Reusable, and Inexpensive Magnesium-Air Fuel Cell
One of the greatest challenges we face today is the sustainable production, storage, and distribution of electrical power. One emerging technology with great promise in this area is that of metal-air fuel cells—a long-term and reusable electricity storage system made from a reactive metal anode and a saline solution. In this study the authors tested several different types of metal to determine which was the most suitable for this application. They found that a fuel cell with a magnesium anode was superior to fuel cells made from aluminum or zinc, producing a voltage and current sufficient for real-world applications such as charging a mobile phone.
Read More...Phytochemical analysis of Annona Reticulata extract and an in-vitro study on its anti-proliferative effects
In this study, the authors investigate the anti-cancer effects of Annona Reticulata (Ramphal or custard apple) by testing whether its extract could inhibit HeLa cell viability.
Read More...Activated NF-κB Pathway in an Irf6-Deficient Mouse Model for Van der Woude Syndrome
Van der Woude syndrome is a common birth defect caused by mutations in the gene Irf6. In this project, students used microarray expression analysis from wild-type and Irf6-deficient mice in order to identify gene networks or pathways differentially regulated due to the Irf6 mutation. They found NF-κB pathway to be activated in deficient mice.
Read More...Battling cultural bias within hate speech detection: An experimental correlation analysis
The authors develop a new method for training machine learning algorithms to differentiate between hate speech and cultural speech in online platforms.
Read More...Floor level estimation using MEMS pressure sensors
The authors propose a method to help first responders find the location of a person within a high-rise building in densely populated areas.
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