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The effects of stress on the bacterial community associated with the sea anemone Diadumene lineata

Cahill et al. | Feb 15, 2021

The effects of stress on the bacterial community associated with the sea anemone Diadumene lineata

In healthy ecosystems, organisms interact in a relationship that helps maintain one another's existence. Stress can disrupt this interaction, compromising the survival of some of the members of such relationships. Here, the authors investigate the effect of stress on the interaction between anemones and their microbiome. Their study suggests that stress changes the composition of the surface microbiome of the anemone D. lineata, which is accompanied by an increase in mucus secretion. Future research into the composition of this stress-induced mucus might reveal useful antimicrobial properties.

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The journey to Proxima Centauri b

Ramaswamy et al. | Apr 01, 2024

The journey to Proxima Centauri b
Image credit: The authors

Someday, rockets from Earth may be launched towards worlds beyond our solar system. But will these rockets be able to reach their destination within a human lifetime? Ramaswamy and Giovinazzi simulate rocket launches to an Earth-like exoplanet to uncover whether it's physically possible to complete the journey within a lifetime.

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Defying chemical tagging: inhomogeneities in the wide binary system HIP 34407/HIP 34426

Còdol et al. | Oct 05, 2023

Defying chemical tagging: inhomogeneities in the wide binary system HIP 34407/HIP 34426
Image credit: Pixabay

This assessed the hypothesis that stars in wide binary systems are chemically homogeneous because of their shared origin. Abundances of the HIP 34407/HIP 34426 binary were obtained by analyzing high-resolution spectra of the system. Discrepancies found in the system’s elemental abundances might be an indicator of the presence of rocky planets around this star. Thus, the differences found in chemical composition might demonstrate limitations in the assumptions of chemical tagging.

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The impact of genetic analysis on the early detection of colorectal cancer

Agrawal et al. | Aug 24, 2023

The impact of genetic analysis on the early detection of colorectal cancer

Although the 5-year survival rate for colorectal cancer is below 10%, it increases to greater than 90% if it is diagnosed early. We hypothesized from our research that analyzing non-synonymous single nucleotide variants (SNVs) in a patient's exome sequence would be an indicator for high genetic risk of developing colorectal cancer.

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Failure of colony growth in probiotic Lactobacillus casei Shirota as result of preservative sorbic acid

Raymond et al. | May 07, 2023

Failure of colony growth in probiotic <i>Lactobacillus casei</i> Shirota as result of preservative sorbic acid

This study tested the proficiency of different concentrations of the antimicrobial sorbic acid to inhibit the probiotic Lactobacillus casei Shirota. It was hypothesized that sorbic acid’s use as a bacterial deterrent would also target this bacterial strain of Lactobacillus. The results supported the hypothesis, with the colony count of L. casei Shirota having significant decreases at all concentrations of sorbic acid. These results additionally suggest that even under the FDA sorbic acid restrictions of 0.03% concentration, damaging effects could be seen in L. casei Shirota.

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Examination of the underlying chemical physics of the Mpemba effect in water and other liquids

Khan et al. | Apr 20, 2023

Examination of the underlying chemical physics of the Mpemba effect in water and other liquids
Image credit: D koi

Counterintuitive in nature, the Mpemba effect asserts that hot liquid freezes faster than cold liquid. While noted throughout history by scientific minds like Aristotle, the phenomenon remains in contention with varying hypotheses for the effect proposed alongside the effect’s rise in popularity. Contributing to the research efforts surrounding the Mpemba effect, the authors in this article explore the effect in different liquids ranging in physical properties and intermolecular forces to determine potential parameters attributable to producing the Mpemba effect.

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Reactivity-informed design, synthesis, and Michael addition kinetics of C-ring andrographolide analogs

Zhou et al. | Nov 17, 2022

Reactivity-informed design, synthesis, and Michael addition kinetics of C-ring andrographolide analogs

Here, based on the identification of androgapholide as a potential therapeutic treatment against cancer, Alzheimer's disease, diabetes, and multiple sclerosis, due to its ability to inhibit a signaling pathway in immune system function, the authors sought ways to optimize the natural product human systems by manipulating its chemical structure. Through the semisynthesis of a natural product along with computational studies, the authors developed an understanding of the kinetic mechanisms of andrographolide and semisynthetic analogs in the context of Michael additions.

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