Arabadopsis, “the fruit fly of plants”, is an easy to grow plant system for genetic manipulation. Here, researchers tested the effects of varied light conditions on plants with specific mutations in the light sensing pathways.
Read More...The Impacts of Varying Types of Light on the Growth of Five Arabidopsis Varieties
Arabadopsis, “the fruit fly of plants”, is an easy to grow plant system for genetic manipulation. Here, researchers tested the effects of varied light conditions on plants with specific mutations in the light sensing pathways.
Read More...Efficient synthesis of superabsorbent beads using photopolymerization with a low-cost method
Superabsorbent beads are remarkable, used throughout our daily lives for various practical applications. These beads, as suggested by their name, possess a unique ability to absorb and retain large quantities of liquids. This characteristic of absorbency makes them essential throughout the medical field, agriculture, and other critical industries as well as in everyday products. To create these beads, the process of photopolymerization is fast growing in favor with distinct advantages of cost efficiency, speed, energy efficiency, and mindfulness towards the environment. In this article, researchers explore the pairing of cheap monomers with accessible equipment for creation of superabsorbent beads via the photopolymerization process. This research substantially demonstrates the successful application of photopolymerization in producing highly absorbent beads in a low-cost context, thereby expanding the accessibility of this process for creating superabsorbent beads in both research and practical applications.
Read More...Effect of mass and center of gravity on vehicle speed and braking performance
In this study, the authors test whether a gravity vehicle, which is a vehicle powered by its own gravity on a ramp, could be designed to move faster when mathematical calculations for optimal mass and center of gravity were applied in the design.
Read More...Low environmental pH inhibits phagosome formation and motility of Tetrahymena pyriformis
In this study, the authors look into some of the implications of rising carbon dioxide levels by studying the effects of acidic pH on the ability of T. pyriformis to feed by quantifying phagosome formation and motility.
Read More...Validation of impact-absorbing football helmet facemask for head injury prevention with simulation
Head injuries are common in American football and the facemasks found on football helmets receive a lot of impact during contacts. This study investigates how effective they are at reducing concussion risk.
Read More...Reactivity-informed design, synthesis, and Michael addition kinetics of C-ring andrographolide analogs
Here, based on the identification of androgapholide as a potential therapeutic treatment against cancer, Alzheimer's disease, diabetes, and multiple sclerosis, due to its ability to inhibit a signaling pathway in immune system function, the authors sought ways to optimize the natural product human systems by manipulating its chemical structure. Through the semisynthesis of a natural product along with computational studies, the authors developed an understanding of the kinetic mechanisms of andrographolide and semisynthetic analogs in the context of Michael additions.
Read More...Spectroscopic Kinetic Monitoring and Molecular Dynamics Simulations of Biocatalytic Ester Hydrolysis in Non-Aqueous Solvent
Lipases are a common class of enzymes that catalyze the breakdown of lipids. Here the authors characterize the the activity of pancreatic lipase in different organic solvents using a choloremetric assay, as well as using molecular dynamic simulations. They report that the activity of pancreatic lipase in 5% methanol is more than 25% higher than in water, despite enzyme stability being comparable in both solvents. This suggests that, for industrial applications, using pancreatic lipase in 5% methanol solution might increase yield, compared to just water.
Read More...DyGS: A Dynamic Gene Searching Algorithm for Cancer Detection
Wang and Gong developed a novel dynamic gene-searching algorithm called Dynamic Gene Search (DyGS) to create a gene panel for each of the 12 cancers with the highest annual incidence and death rate. The 12 gene panels the DyGS algorithm selected used only 3.5% of the original gene mutation pool, while covering every patient sample. About 40% of each gene panel is druggable, which indicates that the DyGS-generated gene panels can be used for early cancer detection as well as therapeutic targets in treatment methods.
Read More...Machine learning-based enzyme engineering of PETase for improved efficiency in plastic degradation
Here, recognizing the recognizing the growing threat of non-biodegradable plastic waste, the authors investigated the ability to use a modified enzyme identified in bacteria to decompose polyethylene terephthalate (PET). They used simulations to screen and identify an optimized enzyme based on machine learning models. Ultimately, they identified a potential mutant PETases capable of decomposing PET with improved thermal stability.
Read More...A new scale of mathematical problem complexity and its application to understanding fear of mathematics
Fear of mathematics is a widespread phenomenon. Pandey and Pandey investigate what this fear has to do with the place of mathematics in a school curriculum, by developing a method for comparing mathematical problem complexity to the complexity of English literature coursework.
Read More...Search articles by title, author name, or tags