Sequence accessibility is an important factor affecting gene expression. Sequence accessibility or openness impacts the likelihood that a gene is transcribed and translated into a protein and performs functions and manifests traits. There are many potential factors that affect the accessibility of a gene. In this study, our hypothesis was that the content of nucleotides in a genetic sequence predicts its accessibility. Using a machine learning linear regression model, we studied the relationship between nucleotide content and accessibility.
Chemicals used in fertilizers and pesticides often end up in nearby bodies of water due to runoff and may have negative impacts on these important ecosystems. In this study, the authors use water containing different nitrogen levels to investigate the effect on the growth of the English daisy.
India’s Digital Public Infrastructure (DPI)—including the Unified Payments Interface (UPI) and Aadhaar—has been globally recognized for advancing financial inclusion and efficient governance. This study analyzes data from 2016–17 to 2023–24 the impact of these services on India's GDP.
Researching gun violence and mass shootings in the U.S. is difficult due to the lack of consistent data collection. Some studies have linked mass shootings to personal financial stress, but little formal research exists on the impact of broader economic conditions. This study hypothesized an inverse relationship between mass shootings and economic performance, using the S&P 500 and unemployment rate as indicators.
The authors looked at different treatments to clean up rainwater collected at home. They found that chlorine treatment and treatment with hydrogen peroxide catalyzed by yeast showed similar potential for cleaning up contaminated rainwater, but that further studies are needed to better assess impact on specific contaminant levels still present.
This study investigates the effects of the PROTAC compound A1874 on CT26 colon carcinoma cells, focusing on its ability to degrade the protein BRD4 and reduce cell viability. While A1874 had previously shown effectiveness in other colon cancer cell lines, its impact on CT26 cells was unknown.
Adolescence is a critical period for self-identity formation, heavily influenced by feedback from social networks. This research examined the interplay between social support from parents and peers and self-concept development in adolescents using data from the National Longitudinal Study of Adolescent to Adult Health. While individual support from parents and peers did not directly impact self-concept, their combined interaction significantly influenced it, highlighting the importance of various social supports in fostering healthy self-concept development and overall adolescent well-being.
Rechargeable batteries are playing an increasingly prominent role in our lives due to the ongoing transition from fossil energy sources to green energy. The purpose of this study was to investigate variables that impact the effectiveness of rechargeable batteries. Alkaline (non-rechargeable) and rechargeable batteries share common features that are critical for the operation of a battery. The positive and negative electrodes, also known as the cathode and anode, are where the energy of the battery is stored. The electrolyte is what facilitates the transfer of cations and anions in a battery to generate electricity. Due to the importance of these components, we felt that a systematic investigation examining the surface area of the cathode and anode as well the impact of electrolytes with different properties on battery performance was justified. Utilizing a copper cathode and aluminum anode coupled with a water in salt electrolyte, a model rechargeable battery system was developed to test two hypotheses: a) increasing the contact area between the electrodes and electrolyte would improve battery capacity, and b) more soluble salt-based electrolytes would improve battery capacity. After soaking in an electrolyte solution, the battery was charged and the capacity, starting voltage, and ending voltage of each battery were measured. The results of this study supported our hypothesis that larger anode/cathodes surface areas and more ionic electrolytes such as sodium chloride, potassium chloride and potassium sulfate resulted in superior battery capacity. Incorporating these findings can help maximize the efficiency of commercial rechargeable batteries.
The authors looked at whether CBD and THC would decrease reproductive rates in a Drosophila melanogaster model. They found that CBD had a greater impact on reducing hatching rates than THC, and that THC resulted in unexpected mortalities.
Athletes with performance anxiety may struggle to play their best and enjoy the game. Various factors may impact how much anxiety an athlete feels, including how much experience they have in the sport. Concha-Ortiz and Navins survey teenage club volleyball players to look for relationships between years of experience and performance anxiety symptoms.
