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The Role of Temporal Lobe Epilepsy in Cardiac Structure and Function

Choi et al. | Aug 15, 2018

The Role of Temporal Lobe Epilepsy in Cardiac Structure and Function

Cardiac autonomic and structural changes may occur in temporal lobe epilepsy patients and contribute to the risk of sudden unexpected death in epilepsy patients. Choi and colleagues reviewed clinical charts to obtain patients’ lifetime seizure count, antiepileptic drug use, and history of heart disease, followed by transthoracic echocardiogram to calculate left ventricle dimensions, ejection fraction, and left ventricle mass. By comparing epilepsy patients to control subjects, they found that epilepsy patients had thinner left ventricle walls and smaller ejection fraction, but with no significant difference in left ventricle mass.

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The Potential of Fibroblast Growth Factors to Stimulate Hair Growth In Vitro

Cheng et al. | Nov 07, 2021

The Potential of Fibroblast Growth Factors to Stimulate Hair Growth In Vitro

Identifying treatments that can stimulate hair growth use could help those struggling with undesirable hair loss. Here, the authors show that Fibroblast Growth Factors can stimulate the division of cells isolated from the mouse hair follicle. Their results suggest that this family of growth factors might be helpful in stimulating hair growth in living animals as well.

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The Effect of Ultraviolet Radiation and the Antioxidant Curcumin on the Longevity, Fertility, and Physical Structure of Drosophila melanogaster: Can We Defend Our DNA?

Lateef et al. | May 18, 2019

The Effect of Ultraviolet Radiation and the Antioxidant Curcumin on the Longevity, Fertility, and Physical Structure of <em>Drosophila melanogaster</em>: Can We Defend Our DNA?

Ultraviolet (UV) radiation is known to alter DNA structure and impair cellular function in all living organisms. In this study, Lateef et al examine the effects of UV radiation to determine whether antioxidant-enriched nutrition can combat the potential deleterious effects of UV radiation on Drosophila melanogaster. They found that UVB (320nm) radiation caused a 59% decrease in the Drosophila lifespan and mutagenic effects on flies' physical appearance, but did not significantly affect fertility. Curcumin significantly prolonged lifespan and enhanced fertility for both UV- and non-UV-exposed flies. The research demonstrates the positive potential of natural antioxidants as weapons against radiation-induced diseases including cancer.

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Formation and sticking of air bubbles in water in d-block containers

Gupta et al. | Jun 21, 2021

Formation and sticking of air bubbles in water in d-block containers

Bubbles! In this study, the authors investigate the effects that different materials, temperature, and distance have on the formation of water bubbles on the surface of copper and steel. They calculated mathematical relations based on the outcomes to better understand whether interstitial hydrogen present in the d-block metals form hydrogen bonds with the water bubbles to account for the structural and mechanical stability.

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The Effect of Concentration on the Pressure of a Sodium Chloride Solution Inside Dialysis Tubing

Dye et al. | Nov 13, 2018

The Effect of Concentration on the Pressure of a Sodium Chloride Solution Inside Dialysis Tubing

In this study, the authors investigate the effects of sodium levels on blood pressure, one of the most common medical problems worldwide. They used a simulated blood vessel constructed from dialysis tubing to carefully analyze pressure changes resulting from various levels of sodium in the external solution. They found that when the sodium concentration in the simulated blood vessel was higher than the external fluid, internal pressure increased, while the reverse was true when the sodium concentration was lower than in the surrounding environment. These results highlight the potential for sodium concentration to have a significant effect on blood pressure in humans by affecting the rate of osmosis across the boundaries of actual blood vessels.

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Strain-selective in vitro and in silico structure activity relationship (SAR) of N-acyl β-lactam broad spectrum antibiotics

Poosarla et al. | Oct 19, 2021

Strain-selective <i>in vitro</i> and <i>in silico</i> structure activity relationship (SAR) of N-acyl β-lactam broad spectrum antibiotics

In this study, the authors investigate the antibacterial efficacy of penicillin G and its analogs amoxicillin, carbenicillin, piperacillin, cloxacillin, and ampicillin, against four species of bacteria. Results showed that all six penicillin-type antibiotics inhibit Staphylococcus epidermidis, Escherichia coli, and Neisseria sicca with varying degrees of efficacy but exhibited no inhibition against Bacillus cereus. Penicillin G had the greatest broad-spectrum antibacterial activity with a high radius of inhibition against S. epidermidis, E. coli, and N. sicca.

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The Effect of Wind Mitigation Devices on Gabled Roofs

Kaufman et al. | Feb 20, 2021

The Effect of Wind Mitigation Devices on Gabled Roofs

The purpose of this study was to test devices installed on a gabled roof to see which reduced the actual uplift forces best. Three gabled birdhouse roofs were each modified with different mitigation devices: a rounded edge, a barrier shape, or an airfoil. The barrier edge had no significant effect on the time for the roof to blow off. The addition of airfoil devices on roofs, specifically in areas that are prone to hurricanes such as Florida, could keep roofs in place during hurricanes, thus reducing insurance bills, overall damage costs, and the loss of lives.

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The Impact of Effective Density and Compressive Strength on the Structure of Crumpled Paper Balls

Chu et al. | Nov 19, 2020

The Impact of Effective Density and Compressive Strength on the Structure of Crumpled Paper Balls

Crumpling is the process whereby a sheet of paper undergoes deformation to yield a three-dimensional structure comprising a random network of ridges and facets with variable density. The authors hypothesized that the more times a paper sheet is crumpled, the greater its compressive strength. Their results show a relatively strong linear relationship between the number of times a paper sheet is crumpled and its compressive strength.

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