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The authors found that treatment with AS20 suppressed phorbol 12-myristate 13-acetate (PMA) and 5-flurouracil (5-FU) induction of COX2 expression. We also observed AS20 treated cells showed DNA fragmentation in HeLa cells.

The authors test potential anti-inflammatory and pro-apoptotic effects of a polyherbal extract formulation on cultured breast cancer cells.

There is a need for safe and effective therapies to prevent platelet aggregation associated with cardiovascular diseases. Prabhakar and Prabhakar test to see whether dietary supplements claiming to reduce cardiovascular disease risk will affect aggregation of human platelets.

In this study, the authors investigate the effect of a herbal formulation on Cyclooxygenase-2 (COX-2) expression in cancer cells. High levels of COX-2 correlates with worsened cancer outcomes and the authors hypothesize that the formulation will inhibit COX-2 levels.

Kashyap Jha et al. look at the formulation of MAT20, a crude extract of the moringa, amla, and tulsi leaves, as a potential complementary and alternative medicine. Using HeLa cells, they find MAT20 up-regulates expression of inflammation and cell cytotoxicity markers. Their data is important for understanding the anti-cancer and anti-inflammatory properties of MAT20.

The authors seek to accelerate wound healing by reducing inflammation with a cocktail containing growth factors and bioactive modulators.