Here, recognizing that alcohol manufacturers may target ethnic minorities and youths with specific forms of advertisements based on previous studies, the authors considered how alcohol storefronts differ depending on the community they are located in. Specifically, they looked at differences between Metro-Dtroit suburban communities of high- and low-incomes. They found that alcohol stores in the low-income areas had more and larger alcohol and malt liquor advertisements per store along with being within 1,000 feet of a school.
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Simulations of Cheetah Roaming Demonstrate the Effect of Safety Corridors on Genetic Diversity and Human-Cheetah Conflict
Ecological corridors are geographic features designated to allow the movement of wildlife populations between habitats that have been fragmented by human landscapes. Corridors can be a pivotal aspect in wildlife conservation because they preserve a suitable habitat for isolated populations to live and intermingle. Here, two students simulate the effect of introducing a safety corridor for cheetahs, based on real tracking data on cheetahs in Namibia.
Read More...Uncovering the hidden trafficking trade with geographic data and natural language processing
The authors use machine learning to develop an evidence-based detection tool for identifying human trafficking.
Read More...The impact of greenhouse gases, regions, and sectors on future temperature anomaly with the FaIR model
This study explores how different economic sectors, geographic regions, and greenhouse gas types might affect future global mean surface temperature (GMST) anomalies differently from historical patterns. Using the Finite Amplitude Impulse Response (FaIR) model and four Shared Socioeconomic Pathways (SSPs) — SSP126, SSP245, SSP370, and SSP585 — the research reveals that future contributions to GMST anomalies.
Read More...A Phylogenetic Study of Conifers Describes Their Evolutionary Relationships and Reveals Potential Explanations for Current Distribution Patterns
Many species of trees are distributed widely around the world, though not always in a way that makes immediate sense. The authors here use genetic information to help explain the geographic distribution of various conifer species throughout the world.
Read More...Using CRISPR technology to inhibit the replication of human cytomegalovirus by deletion of a gene promoter
Human cytomegalovirus (HCMV) causes serious infections in immunocompromised patients and therapies to inhibit latent HCMV are not developed. Using CRISPR/Cas9, the authors were able to delete an important promoter region in HCMV.
Read More...Qualitative tracking of human and animation motions reveals differences in their walking gaits
In their attempt to evoke a greater emotional connection with viewers, animators have strived to replicate human movements in their animations. However, animation movements still appear distinct from human movements. With a focus on walking, we hypothesized that animations, unaffected by real external forces (e.g. gravity), would move with a universally distinct, gliding gait that is discernible from humans.
Read More...The Effect of the Human MeCP2 gene on Drosophila melanogaster behavior and p53 inhibition as a model for Rett Syndrome
In this study, the authors observe if the symptoms of Rett Syndrome, a neurodegenerative disease in humans, are reflected in Drosophila melanogaster. This was achieved by differentiating the behavior and physical aspects of wild-type flies from flies expressing the full-length MeCP2 gene and the mutated MeCP2 gene (R106W). After conducting these experiments, some of the Rett Syndrome symptoms were recapitulated in Drosophila, and a subset of those were partially ameliorated by the introduction of pifithrin-alpha.
Read More...A comparison study in the expansion of human bone marrow mesenchymal stem cells
In this study, the effects of different sources of serum on growing mesenchymal stem cells are compared with the goal of identifying one more suitable for clinical use.
Read More...Estimation of cytokines in PHA-activated mononuclear cells isolated from human peripheral and cord blood
In this study, the authors investigated the time-dependent cytokine secretion ability of phyto-hemagglutinin (PHA)-activated T cells derived from human peripheral (PB) and cord blood (CB). They hypothesized that the anti-inflammatory cytokine, IL-10, and pro-inflammatory cytokine, TNFα, levels would be higher in PHA-activated T cells obtained from PB as compared to the levels obtained from CB and would decrease over time. Upon PHA-activation, the IL-10 levels were relatively high while the TNFα levels decreased, making these findings applicable in therapeutic treatments e.g., rheumatoid arthritis, psoriasis, and organ transplantation.
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