The authors train a neural network to detect text-based emotions including joy, sadness, anger, fear, love, and surprise.
Read More...Training neural networks on text data to model human emotional understanding
The authors train a neural network to detect text-based emotions including joy, sadness, anger, fear, love, and surprise.
Read More...Ocean, atmosphere, and cloud quantity on the surface conditions of tidally-locked habitable zone planets
The authors assessed the atmospheric and oceanic parameters necessary for tidally-locked exoplanets to be habitable.
Read More...The design of Benzimidazole derivatives to bind to GDP-bound K-RAS for targeted cancer therapy
In this study, the authors looked at a proto-oncogene, KRAS, and searched for molecules that are predicted to be able to bind to the inactive form of KRAS. They found that a modified version of Irbesartan, a derivative of benzimidazole, showed the best binding to inactive KRAS.
Read More...Structure-activity relationship of berberine and G4 DNA reveals aromaticity’s effect on binding affinity
Berberine is a natural quaternary alkaloid that has anti-microbial and anti-cancer effects. This compound can bind to Guanine Quadruplex (G4) DNA secondary complexes to help inhibit cancer cell proliferation. In this study, the authors investigate whether incorporating large aromatic rings helps to stabilize berberine-G4 interactions.
Read More...Managing CO2 levels through precipitation-based capture from seawater and electrochemical conversion
The authors set out to develop an electrochemical device that would have efficient and sustained carbon dioxide capture.
Read More...Innovative Treatment for Reducing Senescence and Revitalizing Aging Cells through Gene Silencing
Cellular senescence plays a key role in aging cells and is attributed to a number of disease and pathology. These authors find that genetic editing of both RPS6KB1 and PPARGC1A revitalizes a human skin fibroblast cell line.
Read More...Indoor near-field target detection characteristics under radio and radar joint operation at 2.4 GHz ISM band
In our modern age, the burgeoning use of radios and radars has resulted in competition for electromagnetic spectrum resources. With recent research highlighting solutions to radio and radar mutual interference, there is a desperate need for a cost-effective configuration that permits a radar-radio joint system. In this study, the authors have set out to determine the feasibility of using single-tone continuous-wave radars in a radar-joint system. With this system, they aim to facilitate cost-effective near-field target detection by way of the popularized 2.4-GHz industrial, scientific, and medical (ISM) band.
Read More...A new therapy against MDR bacteria by in silico virtual screening of Pseudomonas aeruginosa LpxC inhibitors
Here, seeking to address the growing threat of multidrug-resistant bacteria (MDR). the authors used in silico virtual screening to target MDR Pseudomonas aeruginosa. They considered a key protein in its biosynthesis and virtually screened 20,000 candidates and 30 derivatives of brequinar. In the end, they identified a possible candidate with the highest degree of potential to inhibit the pathogen's lipid A synthesis.
Read More...Determining surface tension of various liquids and shear modulus of paper using crumpling effect
In this article, the authors investigate the shear modulus of different types of paper in the setting of the crumpling effect.
Read More...Racemic serine is less soluble than pure enantiomers due to stronger intermolecular hydrogen bonds
Seeking to develop a better understanding of the chemical and physical properties of amino acids that compose proteins, here the authors investigated the unusual relative insolubility of racemic mixtures of D- and L-serine compared to the solubility of pure D- or L-serine. The authors used a combination of microscopy and temperature measurements alongside previous X-ray diffraction studies to conclude that racemic DL-serine crystals consist of comparatively stronger hydrogen bond interactions compared to crystals of pure enantiomers. These stronger interactions were found to result in the unique release of heat during the crystallization of racemic mixtures.
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