This manuscript was retracted on March 22, 2021 as it did not adhere to JEI's submission requirements with respect to author permissions. All authors on the manuscript agreed to its removal.
Read More...RETRACTED: Effect of Curcumin on Motor Behaviors in Drosophila melanogaster PINK1 Mutant Parkinson’s Model
This manuscript was retracted on March 22, 2021 as it did not adhere to JEI's submission requirements with respect to author permissions. All authors on the manuscript agreed to its removal.
Read More...Expression of Anti-Neurodegeneration Genes in Mutant Caenorhabditis elegans Using CRISPR-Cas9 Improves Behavior Associated With Alzheimer’s Disease
Alzheimer's disease is one of the leading causes of death in the United States and is characterized by neurodegeneration. Mishra et al. wanted to understand the role of two transport proteins, LRP1 and AQP4, in the neurodegeneration of Alzheimer's disease. They used a model organism for Alzheimer's disease, the nematode C. elegans, and genetic engineering to look at whether they would see a decrease in neurodegeneration if they increased the amount of these two transport proteins. They found that the best improvements were caused by increased expression of both transport proteins, with smaller improvements when just one of the proteins is overly expressed. Their work has important implications for how we understand neurodegeneration in Alzheimer's disease and what we can do to slow or prevent the progression of the disease.
Read More...What’s in a Name? Do Labels Influence People’s Liking for Cookies?
Previous studies have found that how a food item is labeled may influence people's liking of it. This study used a cookie taste test to investigate whether people's liking of a dessert item would be swayed by the use of different labels.
Read More...Testing antimicrobial properties of common household spices in a real-world scenario
In this article the authors look at the ability of spices to reduce microbial load on a cutting surface by comparing growth of bacteria cultured before and after cleaning with various spice mixtures.
Read More...Evaluating Biomarkers and Treatments for Acute Kidney Injury in a Zebrafish Model
Coronary Artery Disease (CAD) is the leading cause of death in the United States, and 81% of Acute Kidney Injury (AKI) patients in the renal fibrosis stage later develop CAD. In this study, Mathew and Joykutty aimed to create a cost-effective strategy to treat AKI and thus prevent CAD using a model of the zebrafish, Danio rerio. They first tested whether AKI is induced in Danio rerio upon exposure to environmental toxins, then evaluated nitrotyrosine as an early biomarker for toxin-induced AKI. Finally, they evaluated 4 treatments of renal fibrosis, the last stage of AKI, and found that the compound SB431542 was the most effective treatment (reduced fibrosis by 99.97%). Their approach to treating AKI patients, and potentially prevent CAD, is economically feasible for translation into the clinic in both developing and developed countries.
Read More...Mapping QTLs for Popping Ability in a Popcorn × Dent Maize Genetic Cross
Have you ever wondered what contributes to the popping ability of popcorn? In this study, the authors use Quantitative Trait Locus (QTL) mapping to identify genes that may contribute to specific popping characteristics including kernel size and popping expansion volume (PEV).
Read More...Evaluating cinnamaldehyde as an antibacterial agent in a produce wash for leafy greens
Recognizing a growing demand for organic produce, the authors sought to investigate plant-based antibiotic solutions to meet growing consumer demand for safe produce and also meet microbial standards of the USDA. The authors investigated the use of cinnamaldehyde as an antibacterial again E. coli, finding that lettuce treated with cinnamaldehyde displayed significantly lower colony-forming units of E. coli when compared to lettuce treated with chlorine bleach.
Read More...LawCrypt: Secret Sharing for Attorney-Client Data in a Multi-Provider Cloud Architecture
In this study, the authors develop an architecture to implement in a cloud-based database used by law firms to ensure confidentiality, availability, and integrity of attorney documents while maintaining greater efficiency than traditional encryption algorithms. They assessed whether the architecture satisfies necessary criteria and tested the overall file sizes the architecture could process. The authors found that their system was able to handle larger file sizes and fit engineering criteria. This study presents a valuable new tool that can be used to ensure law firms have adequate security as they shift to using cloud-based storage systems for their files.
Read More...The Effect of Cobalt Biomineralization on Power Density in a Microbial Fuel Cell
A microbial fuel cell is a system to produce electric current using biochemical products from bacteria. In this project authors operated a microbial fuel cell in which glucose was oxidized by Shewanella oneidensis in the anodic compartment. We compared the power output from biomineralized manganese or cobalt oxides, reduced by Leptothrix cholodnii in the cathodic compartment.
Read More...Identifying the wavelength that generates the most voltage and current in a solar panel
A key barrier to adoption of solar energy technology is the low efficiency of solar cells converting solar energy into electricity. Sims and Sims tackle this problem by coding a Raspberry Pi as a multimeter to determine which wavelength of light generates the most voltage and current from a solar panel.
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