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Investigating the Role of the Novel ESCRT-III Recruitment Factor CCDC11 in HIV Budding: A Potential Target for Antiviral Therapy

Takemaru et al. | Feb 24, 2020

Investigating the Role of the Novel ESCRT-III Recruitment Factor CCDC11 in HIV Budding: A Potential Target for Antiviral Therapy

Acquired immunodeficiency syndrome (AIDS) is a life-threatening condition caused by the human immunodeficiency virus (HIV). In this work, Takemaru et al explored the role of Coiled-Coil Domain-Containing 11 (CCDC11) in HIV-1 budding. Their results suggest that CCDC11 is critical for efficient HIV-1 budding, potentially indicating CCDC11 a viable target for antiviral therapeutics without major side effects.

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Associations between substance misuse, social factors, depression, and anxiety among college students

Kouser et al. | Jun 12, 2023

Associations between substance misuse, social factors, depression, and anxiety among college students
Image credit: Jordan Encarnacao

Here, the authors considered the effects of relationship status and substance use on the mental health of colleges students, where they specifically examined their correlation with depression, anxiety, and the fear of missing out (FoMO). Through a survey of college students they found that those with higher substance misuse had higher levels of anxiety, depression, and FoMO, while those involved in longer-term relationships had lower levels of FoMo and alcohol use.

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Characterization and Phylogenetic Analysis of the Cytochrome B Gene (cytb) in Salvelinus fontinalis, Salmo trutta and Salvelinus fontinalis X Salmo trutta Within the Lake Champlain Basin

Palermo et al. | Jan 24, 2014

Characterization and Phylogenetic Analysis of the Cytochrome B Gene (<em>cytb</em>) in <em>Salvelinus fontinalis</em>,<em> Salmo trutta</em> and <em>Salvelinus fontinalis X Salmo trutta</em> Within the Lake Champlain Basin

Recent declines in the brook trout population of the Lake Champlain Basin have made the genetic screening of this and other trout species of utmost importance. In this study, the authors collected and analyzed 21 DNA samples from Lake Champlain Basin trout populations and performed a phylogenetic analysis on these samples using the cytochrome b gene. The findings presented in this study may influence future habitat decisions in this region.

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