In this study, the authors test whether excess copper exposure has neurobehavioral effects on Hirudo verbana leeches.

The authors test the effects of common food industry preservatives on the heart rate of the freshwater crustacean Daphnia magna.

Here, seeking to better understand the roles of glycans in the receptors of active sites of neuronal cells, the authors used molecular dynamics simulations to to uncover the dynamic nature of N-glycans on membrane proteins. The authors suggest the study of theinteractions of these membrane poreins could provide future potential therapeutic targets to treat mental diseases.

The Scripps National Spelling Bee (SNSB) is an iconic academic competition for United States (US) schoolchildren, held annually since 1925. However, the sizes and geographic distributions of sponsored regions are uneven. One state may send more than twice as many spellers as another state, despite similar numbers in child population. In 2018, the SNSB introduced a wildcard program known as RSVBee, which allowed students to apply to compete as a national finalist, even if they did not win their regional spelling bee. In this study, the authors tested the hypothesis that the geographic distribution of SNSB national finalists more closely matched the child population of the US after RSVBee was implemented.

Each day we are flooded with new items that promise us a better experience at a better price. This forces buyers to continuously chose between sticking to what they know, or trying something new. In turn, companies need to be aware of the factors affecting consumer choices, that too within the different fractions of society. In this study the authors investigate the effect of survey-based price setting on profits made based on African American teen purchases, and how African-American teen loyalty to a particular brand affects their willingness to pay a higher price than the market average for their preferred brand items.

Neural machine translation (NMT) is a software that uses neural network techniques to translate text from one language to another. However, one of the most famous NMT models—Google Translate—failed to give an accurate English translation of a famous Korean nursery rhyme, "Airplane" (비행기). The authors fine-tuned a pre-trained model first with a dataset from the lyrics domain, and then with a smaller dataset containing the rhythmical properties, to teach the model to translate rhythmically accurate lyrics. This stacked fine-tuning method resulted in an NMT model that could maintain the rhythmical characteristics of lyrics during translation while single fine-tuned models failed to do so.

Here, the authors investigated if dietary Omega-3 fatty acids could reduce the potential for cerebral cavernous malformations, which are brain lesions that occur due to a genetic mutation where high membrane permeability occurs between endothelial cell junctions. In a bovine-based study where some cows were fed an Omega-3 diet, the authors found the membranes of bovine blood cells increased in thickness with Omega-3 supplementation. As a result, they suggest that dietary Omega-3 could be considered as a possible preventative measure for cerebral cavernous malformations.

Gun violence has been a serious issue in the South Side of Chicago for a long time. To intervene, regulators have passed legislation they hoped to curb -if not completely eradicate- the issue. However, there is little analysis done on how effective the various laws have been at reducing gun violence. Here the authors explore the association between firearm purchase laws passed between 1993-2018 and the incidence of gun homicide in Chicago's South Side. Their analysis suggests that some laws have been more effective than others, while some might have exacerbated the issue. However, they do not consider other contributing factors, which makes it difficult to prove causation without further investigation.

In this study the author undertakes a careful characterization of a special type of chemical reaction, called an oscillating Belousov-Zhabotinsky (or B-Z) reaction, which has a number of existing applications in biomedical engineering as well as the potential to be useful in future developments in other fields of science and engineering. Specifically, she uses experimental measurements in combination with computational analysis to investigate whether the reaction is cohesive – that is, whether the oscillations between chemical states will remain consistent or change over time as the reaction progresses. Her results indicate that the reaction is not cohesive, providing an important foundation for the development of future technologies using B-Z reactions.

With disruption of DNA repair pathways pertinent to the timeline of cancer, thorough evaluation of mutations relevant to DNA repair proteins is crucial within cancer research. One such mutation includes S815L PMS2 - a mutation that results in significant decrease of DNA repair function by PMS2 protein. While mutation of PMS2 is associated with significantly increased colorectal and endometrial cancer risk, much work is left to do to establish the functional effects of the S815L PMS2 mutation in ovarian cancer progression. In this article, researchers contribute to this essential area of research by uncovering the tumor-progressive effects of the S815L PMS2 mutation in the context of ovarian cancer cell lines.