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Significance of Tumor Growth Modeling in the Behavior of Homogeneous Cancer Cell Populations: Are Tumor Growth Models Applicable to Both Heterogeneous and Homogeneous Populations?

Reddy et al. | Jun 10, 2021

Significance of Tumor Growth Modeling in the Behavior of Homogeneous Cancer Cell Populations: Are Tumor Growth Models Applicable to Both Heterogeneous and Homogeneous Populations?

This study follows the process of single-cloning and the growth of a homogeneous cell population in a superficial environment over the course of six weeks with the end goal of showing which of five tumor growth models commonly used to predict heterogeneous cancer cell population growth (Exponential, Logistic, Gompertz, Linear, and Bertalanffy) would also best exemplify that of homogeneous cell populations.

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Differential privacy in machine learning for traffic forecasting

Vinay et al. | Dec 21, 2022

Differential privacy in machine learning for traffic forecasting

In this paper, we measured the privacy budgets and utilities of different differentially private mechanisms combined with different machine learning models that forecast traffic congestion at future timestamps. We expected the ANNs combined with the Staircase mechanism to perform the best with every value in the privacy budget range, especially with the medium high values of the privacy budget. In this study, we used the Autoregressive Integrated Moving Average (ARIMA) and neural network models to forecast and then added differentially private Laplacian, Gaussian, and Staircase noise to our datasets. We tested two real traffic congestion datasets, experimented with the different models, and examined their utility for different privacy budgets. We found that a favorable combination for this application was neural networks with the Staircase mechanism. Our findings identify the optimal models when dealing with tricky time series forecasting and can be used in non-traffic applications like disease tracking and population growth.

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Developing novel plant waste-based hydrogels for skin regeneration and infection detection in diabetic wounds

Mathew et al. | Aug 10, 2023

Developing novel plant waste-based hydrogels for skin regeneration and infection detection in diabetic wounds

The purpose of this investigation is to develop a hydrogel to aid skin regeneration by creating an extracellular matrix for fibroblast growth with antibacterial and infection-detection properties. Authors developed two natural hydrogels based on pectin and potato peels and characterized the gels for fibroblast compatibility through rheology, scanning electron microscopy, swelling, degradation, and cell cytotoxicity assays. Overall, this experiment fabricated various hydrogels capable of acting as skin substitutes and counteracting infections to facilitate wound healing. Following further testing and validation, these hydrogels could help alleviate the 13-billion-dollar financial burden of foot ulcer treatment.

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The Effect of Lyrical and Instrumental Music on Reading Comprehension Tasks

Herring et al. | Nov 01, 2018

The Effect of Lyrical and Instrumental Music on Reading Comprehension Tasks

Herring and Scott investigated how specific types of background music affected 8th and 9th graders' performance on a reading comprehension task. In the study, their results indicated that music with English lyrics led to lower reading comprehension scores, while foreign language and instrumental music was comparable to no music at all. The authors therefore recommend that teachers avoid playing English language music for students completing reading tasks in order to minimize distractions and improve work efficiency.

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Do Initial Strategies or Choice of Piece Color Lead to Advantages in Chess Games?

Ponnaluri et al. | Feb 07, 2017

Do Initial Strategies or Choice of Piece Color Lead to Advantages in Chess Games?

White pieces make the first move in chess games, and there are several opening strategies and consequent defense strategies that white and black pieces, respectively, can take . The author of this paper investigated whether taking a specific opening and defense strategy, as well as playing as white vs. black, can increase the chances of winning the game, by playing against various human and computer opponents.

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Effect of Collagen Gel Structure on Fibroblast Phenotype

Grace et al. | Nov 28, 2012

Effect of Collagen Gel Structure on Fibroblast Phenotype

Environment affects the progression of life, especially at the cellular level. This study investigates multiple 3-dimensional growth environments, also known as scaffolds or hydrogels, and their effect on the growth of a type of cells called fibroblasts. These results suggest that a scaffold made of collagen and polyethylene glycol are favorable for cell growth. This research is useful for developing implantable devices to aid wound healing.

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Comparing the Effectiveness of Popular Treatments for Swelling and Scarring

Benavides et al. | Jul 08, 2020

Comparing the Effectiveness of Popular Treatments for Swelling and Scarring

Numerous specialty treatments claim to reduce swelling and scarring; however, it is unknown if these treatments are more effective than less expensive treatments. In an attempt to determine if one outperforms the other, treatments were applied to the same subject following bilateral orthopedic foot surgery. No difference was found the specialty treatments compared to more cost-effective treatments.

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