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Inhibiting the ERK pathway and the TRPM7 ion channel in gastric and bladder cancer cells

Yang et al. | Oct 14, 2021

Inhibiting the ERK pathway and the TRPM7 ion channel in gastric and bladder cancer cells

In this work the authors investigate new possible treatment methods for gastric and bladder cancers. They specifically targeted the transient receptor potential cation subfamily M member 7 (TRPM7), an ion channel that plays an important role in the survival of both of these cancers, and extracellular regulated kinases (ERKs),which contributes to the carcinogenesis of many cancers including gastric cancer. As a result, the authors consider the effects of Ginsenoside Rd, NS8593, curcumin, and icariin , known to inhibit TRPM7 and ERK. The authors found that these treatments decrease proliferation and induce apoptosis in studies of gastric and bladder cancer cells.

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Changing public opinions on genetically modified organisms through access to educational resources

Klein et al. | Jul 26, 2022

Changing public opinions on genetically modified organisms through access to educational resources

Genetically modified organisms (GMOs) are crops or animals that have been genetically engineered to express a certain physical or biological characteristic and have various benefits that have made them become increasingly popular. However, the public has had mixed reactions to the use of GMOs, with some skeptical of their safety. The purpose of this study was to evaluate how opinions on genetically modified foods can change from exposure to small amounts of information

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Optimizing Interplanetary Travel Using a Genetic Algorithm

Murali et al. | Oct 28, 2018

Optimizing Interplanetary Travel Using a Genetic Algorithm

In this work, the authors develop an algorithm that solves the problem of efficient space travel between planets. This is a problem that could soon be of relevance as mankind continues to expand its exploration of outer space, and potentially attempt to inhabit it.

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Factors Influencing Muon Flux and Lifetime: An Experimental Analysis Using Cosmic Ray Detectors

Samson et al. | May 18, 2020

Factors Influencing Muon Flux and Lifetime: An Experimental Analysis Using Cosmic Ray Detectors

Muons, one of the fundamental elementary particles, originate from the collision of cosmic rays with atmospheric particles and are also generated in particle accelerator collisions. In this study, Samson et al analyze the factors that influence muon flux and lifetime using Cosmic Ray Muon Detectors (CRMDs). Overall, the study suggests that water can be used to decrease muon flux and that scintillator orientation is a potential determinant of the volume of data collected in muon decay studies.

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Pollination Patterns by Green-Backed Firecrown Hummingbirds

Freeland et al. | May 28, 2020

Pollination Patterns by Green-Backed Firecrown Hummingbirds

The Green-backed Firecrown hummingbird is an essential pollinator in the temperate rainforests of southern South America. However, little is known about the ecology of these birds. Authors examined the foraging patterns of these birds identifying interesting differences in foraging patterns among season, age and sex.

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Utilizing a novel T1rho method to detect spinal degeneration via magnetic resonance imaging

Wang et al. | Oct 04, 2023

Utilizing a novel T1rho method to detect spinal degeneration via magnetic resonance imaging

Spinal degeneration has been linked to critical conditions such as osteoarthritis in adults aged 40+; while this condition is considered to be irreversible, we took interest in magnetic resonance imaging (MRI) for early detection of the condition. Ultimately, our purpose was to determine the effectiveness of a relatively novel T1rho method in the early detection of spinal degeneration, and we hypothesized that the early to mild progression of spinal degeneration would affect T1rho values following an MRI scan.

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Integrated Ocean Cleanup System for Sustainable and Healthy Aquatic Ecosystems

Anand et al. | Nov 14, 2020

Integrated Ocean Cleanup System for Sustainable and Healthy Aquatic Ecosystems

Oil spills are one of the most devastating events for marine life. Finding ways to clean up oil spills without the need for harsh chemicals could help decrease the negative impact of such spills. Here the authors demonstrate that using a combination of several biodegradable substances can effectively adsorb oil in seawater in a laboratory setting. They suggest further exploring the potential of such a combination as a possible alternative to commonly-used non-biodegradable substances in oil spill management.

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The Bioactive Ingredients in Niuli Lactucis Agrestibus Possess Anticancer Effects

Zhu et al. | Sep 17, 2019

The Bioactive Ingredients in Niuli Lactucis Agrestibus Possess Anticancer Effects

In​ the​ field​ of​ medicine,​ natural​ treatments​ are​ becoming ​increasingly ​vital ​towards ​the ​cure ​of ​cancer. Zhu et al. wanted to investigate the effects of lettuce extract on cancer cell survival and proliferation. They used an adenocarcinoma cell line, COLO320DM, to determine whether crude extract from a lettuce species called Niuli​ Lactucis Agrestibus​ would affect cancer cell survival, migration, and proliferation. They found that Niuli extract inhibited cancer cell survival, increased expression of cell cycle inhibitors p21 and p27, and inhibited migration. However, Niuli extract did not have these effects on healthy cells. This work reveals important findings about a potential new source of anti-colorectal cancer compounds.

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Mask wearing and oxyhemoglobin saturation effects during exercise

Foss et al. | Jul 15, 2022

Mask wearing and oxyhemoglobin saturation effects during exercise

Wearing face masks has become a common occurrence in everyday life and during athletics due to the spread of diseases. This study tested if masks would affect blood percent saturation of hemoglobin (SpO2) during treadmill exercise. The data analysis showed that mask type, time, and the interaction of mask type and time were significant results, regardless of physical ability. These results may assist athletes in understanding the differences between training and competing with and without a mask.

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