In this study, the authors investigate whether phototaxis and odortaxis in Drosophila melanogaster occurs through linear summation of cues including light and attractive odorants.
Read More...Linear and non-linear summation of responses to visual and olfactory cues in male Drosophila melanogaster
In this study, the authors investigate whether phototaxis and odortaxis in Drosophila melanogaster occurs through linear summation of cues including light and attractive odorants.
Read More...TNF signaling pathway upregulation as a potential pharmaceutical target for cocaine-addicted individuals
In this article, the authors investigate the RNA expression differences between groups of chronic cocaine abusers and drug-free subjects.
Read More...Manipulation of extracellular matrix mechanical cues to stimulate oligodendrocytes to promote remyelination
Oligodendrocytes are specialized brain cells that can change to cells that produce myelin and protect nerves. This study investigates the capacity for different extracellular matrix cues to induce this effect in culture.
Read More...Investigating the Role of the Novel ESCRT-III Recruitment Factor CCDC11 in HIV Budding: A Potential Target for Antiviral Therapy
Acquired immunodeficiency syndrome (AIDS) is a life-threatening condition caused by the human immunodeficiency virus (HIV). In this work, Takemaru et al explored the role of Coiled-Coil Domain-Containing 11 (CCDC11) in HIV-1 budding. Their results suggest that CCDC11 is critical for efficient HIV-1 budding, potentially indicating CCDC11 a viable target for antiviral therapeutics without major side effects.
Read More...Stress-induced genetic memory inheritance and retention in Planarian biological model
This study explored whether planaria, known for their regenerative abilities, can retain learned memories after regeneration and how stressors like alcohol affect memory.
Read More...Paralyzing effects of CO2 and hypothermia on Madagascar hissing and dubia cockroaches
Here the authors sought to find a more ethical and efficient way to temporary paralyze a cockroach by comparing the results of two methods. By comparing immobilization through immersion in cold water and exposure to a 100 % CO2 environment, they found that cockroaches could be immobilized and recovered significantly faster when exposed to CO2.
Read More...Varying levels of disinfectant resistance among invasive Klebsiella pneumoniae isolates
The authors identify disinfectant-resistant bacterial strains of infection-causing bacteria from samples collected at a hospital setting.
Read More...Differential MERS-CoV response in different cell types
The authors compare RNA expression profiles across three human cell types following infection with MERS-CoV
Read More...A Novel Alzheimer's Disease Therapeutic Model: Attenuating Hyperphosphorylated Tau and Amyloid β (Aβ) Aggregates by Characterizing Antioxidative, Anti-Inflammatory, and Neuroprotective Properties of Natural Extracts
Oxidative damage and neuro-inflammation were the key pathways implicated in the pathogenesis of Alzheimer’s disease. In this study, 30 natural extracts from plant roots and leaves with extensive anti-inflammatory and anti-oxidative properties were consumed by Drosophila melanogaster. Several assays were performed to evaluate the efficacy of these combinational extracts on delaying the progression of Alzheimer’s disease. The experimental group showed increased motor activity, improved associative memory, and decreased lifespan decline relative to the control group.
Read More...Lack of correlation between odor composition and neuron response in the olfactory cortex of mice
To address whether odor sensory circuits are organized topographically, the authors investigate whether the neuronal responses to similar odors amongst different mice mapped similarly in brain.
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