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Down-regulation of CD44 inhibits Wnt/β-catenin mediated cancer cell migration and invasion in gastric cancer

Baek et al. | May 10, 2021

Down-regulation of CD44 inhibits Wnt/β-catenin mediated cancer cell migration and invasion  in gastric cancer

In this study, we aimed to characterize CD44-mediated regulation of the Wnt/β-catenin signaling pathway, which promotes cancer invasion and metastasis. We hypothesized that CD44 down-regulation will inhibit gastric cancer cell migration and invasion by leading to down-regulation of Wnt/β-catenin signaling. We found that CD44 up-regulation was significantly related to poor prognosis in gastric cancer patients. We demonstrated the CD44 down-regulation decreased β-catenin protein expression level. Our results suggest that CD44 down-regulation inhibits cell migration and invasion by down-regulating β-catenin expression level.

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Comparative Gamma Radiation Analysis by Geographic Region

Zadan et al. | Jul 20, 2015

Comparative Gamma Radiation Analysis by Geographic Region

Gamma radiation can be produced by both natural and man-made sources and abnormally high exposure levels could lead to an increase in cell damage. In this study, gamma radiation was measured at different locations and any correlation with various geographic factors, such as distance from a city center, elevation and proximity to the nearest nuclear reactor, was determined.

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Performance of Panicum virgatum Cultivars in Competition With Bromus inermis and Differing Amounts of N Fertilizer

Ferris et al. | Mar 04, 2019

Performance of <em>Panicum virgatum</em> Cultivars in Competition With <em>Bromus inermis</em> and Differing Amounts of N Fertilizer

With growing demands for ethanol, many researchers are turning to Panicum virgatum (switchgrass) as a feedstock of cellulosic ethanol. In this study, Ferris and Gillan examine the germination, biomass, nitrogen, survival, and chlorophyll absorbance of two switchgrass cultivars of grown in competition with Bromus inermis (smooth brome) with two varying levels of nitrogen fertilizer. Results presented indicate that during establishment, competition from other species has a greater effect than nitrogen fertilizer.

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Temperatures of 20°C Produce Increased Net Primary Production in Chlorella sp.

Biddinger et al. | Feb 25, 2020

Temperatures of 20°C Produce Increased Net Primary Production in <em>Chlorella sp.</em>

Chlorella sp. are unicellular green algae that use photosynthesis to reduce carbon dioxide into glucose. In this study, authors sought to determine the temperature that Chlorella sp. is maximally efficient at photosynthesis, and therefore removing the most carbon dioxide from the system. This activity could be harnessed to naturally remove carbon dioxide from the environment, fighting the effects of climate change.

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