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The Effects of Antibiotics on Nutrient Digestion

Murea et al. | Oct 06, 2017

The Effects of Antibiotics on Nutrient Digestion

One disadvantage of antibiotic therapy is the potential for unpleasant gastrointestinal side effects. Here, the authors test whether some common antibiotics directly interfere with the digestion of protein, fat, or sugars. This study provides motivation to more carefully investigate the interactions between antibiotics and gut enzymes in order to inform treatment decisions and improve patient outcomes.

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The effects of the cancer metastasis promoting gene CD151 in E. coli

Burgess et al. | Jun 11, 2023

The effects of the cancer metastasis promoting gene <i>CD151</i> in <i>E. coli</i>
Image credit: qimono

The independent effects of metastasis-promoting gene CD151 in the process of metastasis are not known. This study aimed to isolate CD151 to discover what its role in metastasis would be uninfluenced by potential interactions with other components and pathways in human cells. Results showed that CD151 significantly increased the adhesion of the cells and decreased their motility. Thus, it may be that CD151 is upregulated in cancer cells for the last step of metastasis, and it increases the chances of success of metastasis by aiding in implantation of the cancer cells. Targeting CD151 in chemotherapeutic modalities could therefore potentially slow or prevent metastasis.

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Applying centrality analysis on a protein interaction network to predict colorectal cancer driver genes

Saha et al. | Nov 18, 2023

Applying centrality analysis on a protein interaction network to predict colorectal cancer driver genes

In this article the authors created an interaction map of proteins involved in colorectal cancer to look for driver vs. non-driver genes. That is they wanted to see if they could determine what genes are more likely to drive the development and progression in colorectal cancer and which are present in altered states but not necessarily driving disease progression.

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Analysis of Patterns in the Harmonics of a String with Artificially Enforced Nodes

Jain et al. | Jan 28, 2021

Analysis of Patterns in the Harmonics of a String with Artificially Enforced Nodes

This study examines the higher harmonics in an oscillating string by analyzing the sound produced by a guitar with a spectrum analyzer. The authors mathematically hypothesized that the higher harmonics in the series of the directly excited 2nd harmonic contain the alternate frequencies of the fundamental series, the higher harmonics of the directly excited 3rd harmonic series contain every third frequency of fundamental series, and so on. To test the hypotheses, they enforced artificial nodes to excite the 2nd, 3rd, and 4th harmonics directly, and analyzed the resulting spectrum to verify the mathematical hypothesis. The data analysis corroborates both hypotheses.

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The Effect of Cooking Method on the Amount of Fat in an Egg

Srinivasan et al. | Dec 01, 2014

The Effect of Cooking Method on the Amount of Fat in an Egg

Fat can be chemically altered during cooking through a process called lipid oxidation, which can have a negative impact on health. In this study, the authors measured the extracted fat in raw, fried and hard-boiled eggs and found that cooking eggs to a higher temperature resulted in a lower amount of extracted fat, indicating a greater amount of oxidized fat.

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Estimation of Reproduction Number of Influenza in Greece using SIR Model

Skarpeti et al. | Nov 18, 2020

Estimation of Reproduction Number of Influenza in Greece using SIR Model

In this study, we developed an algorithm to estimate the contact rate and the average infectious period of influenza using a Susceptible, Infected, and Recovered (SIR) epidemic model. The parameters in this model were estimated using data on infected Greek individuals collected from the National Public Health Organization. Our model labeled influenza as an epidemic with a basic reproduction value greater than one.

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Identification of potential therapeutic targets for multiple myeloma by gene expression analysis

Kochenderfer et al. | Apr 26, 2024

Identification of potential therapeutic targets for multiple myeloma by gene expression analysis
Image credit: The authors

A central challenge of cancer therapy is identifying treatments that will effectively target cancer cells while minimizing effects on healthy cells. To identify potential targets for treating a multiple myeloma, a frequently incurable cancer, Kochenderfer and Kochenderfer analyze RNA sequencing data from the Cancer Cell Line Encyclopedia to find genes with high expression in multiple myeloma cells and low expression in normal tissues

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Osmotic characteristics of water retention structures of Bursera microphylla in relation to soil salinity

Groom et al. | Jul 12, 2023

Osmotic characteristics of water retention structures of <i>Bursera microphylla</i> in relation to soil salinity
Image credit: Lisa Fotios

This study hypothesized that sodium chloride was taken up through plant root structures to facilitate water transportation, and that sodium chloride accumulation was directly proportional to the soil salinity. Results showed that most cells within the “bulb” structures were isotonic at a concentration approximately twice as high as that of root tissue and ambient soil salinity, therefore supporting the presented hypothesis.

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High school students show some reluctance to COVID-19 guidelines

Basit Abid et al. | Jun 25, 2024

High school students show some reluctance to COVID-19 guidelines
Image credit: The authors

COVID-19 has officially been downgraded from the status of a global health emergency, but have COVID-19 safety practices become a new way of life for students? The authors collected survey data on COVID-19-related knowledge and behaviors of high-school students in Punjab, Pakistan and Santa Clara County, California, USA, so see where high-schoolers stand on pandemic safety today.

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Which fruit peel helps retain the most soil moisture?

Parashar et al. | Jan 09, 2024

Which fruit peel helps retain the most soil moisture?
Image credit: Anshu A

Here, the authors investigated the ability to use fruit peels to help soil retain moisture, a property that is essential to agriculture. Across a 96-hour observation period, orange, banana, and kiwi peel water emulsions were evaluated for their effects on soil moisture. They found that orange peels retained the most moisture, but banana and kiwi peels also offered improvements over their control sample.

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