Chronic wounds pose a serious threat to an individual’s health and quality of life. However, due to the severity and morbidity of such wounds, many pre-existing treatments are inefficient or costly. While the use of skin grafts and other such biological constructs in chronic wound healing has already been characterized, the use of umbilical cord tissue has only recently garnered interest, despite the cytokine-rich composition of Wharton’s jelly (cord component). Our current study aimed to characterize the use of an umbilical cord derived conditioned medium (UC-CM) to treat chronic wounds.
In this study, we performed orthotopic auto-transplantation of fresh ovarian tissues by transplanting unilateral half ovarian tissue to the contralateral ovary in the ICR (Institute of Cancer Research) strain of outbred, heterogeneous mice to determine if the transplanted tissue could be functional. We found that the freshly transplanted mouse ovarian tissue survived and functional, as histochemical and immunofluorescence assays have shown that not only both follicles at different developing stages and corpus luteum are available, but the morphology of them are properly maintained within the transplanted tissue.
Each year, large amounts of carcinogenic pollutants are released into the environment, which negatively affects human health. This study ranks the major carcinogenic pollutants that are released into the air, water, and land by both the total released amounts and the potential carcinogenic risks.
The authors investigated an important parasite-host relationship between the raccoon roundworm and the raccoon to understand how parasite prevalence is affected by location. They found that the parasite infection was more prevalent in raccoons found closer to human dwellings, though the number of roundworm eggs was not significantly different. These results are important human health, since roundworm infection is lethal to humans and can be transmitted from raccoons to humans - the authors suggest that more research into this parasite and awareness of its prevalence is needed to prevent disease.
Palermo et al. examined the effect of group size on drinking habits of college and high school students. The authors found that both high school and college students tended to consume the most alcohol in group sizes of 4 or more, independent of how frequently they drink. They also found that the proportion of college students that drink is nearly twice the proportion of high school students that drink. This study supports previous findings that underage drinking happens in large groups and suggests that effective intervention in underage drinking would be at the group level.
This study examined the ability of copper and copper alloy surfaces to inhibit bacterial growth, which may be help prevent healthcare-associated infections. The authors exposed two non-pathogenic strains of bacteria to different metal plates for varying degrees of time and measured bacterial growth.
Honey possesses distinctive antimicrobial properties; however, it is unknown which compounds in honey are responsible for these properties. In this research study, Abdel-Azim et al. examine the role of osmotic stress in honey and the antibacterial efficacy of both Manuka and raw pasture honey.
While resources on the safety of household cleaning products are plentiful, measures of efficacy of these cleaning chemicals against bacteria and viruses remain without standardization in the consumer market. The COVID pandemic has exasperated this knowledge gap, stoking the growth of misinformation and misuse surrounding household cleaning chemicals. Arriving at a time dire for sanitization standardization, the authors of this paper have created a quantifying framework for consumers by comparing a wide range of household cleaning products in their efficacy against bacteria generated by a safe and easily replicable yogurt model.
The COVID-19 pandemic demonstrated the depth and significance of healthcare inequality in the United States. Xiao, Xiao, and Gong examine healthcare disparities in the Richmond (Virginia) metropolitan area by analyzing whether people from disadvantaged populations must travel for longer to reach healthcare facilities.
Rhizopus stolonifer is a mold commonly found growing on bread that can cause many negative health effects when consumed. Preservatives are the well-known answer to this problem; however, many preservatives are not naturally found in food, and some have negative health effects of their own. We focused on honey as a possible solution because of its natural origin and self-preservation ability. We hypothesized that honey would decrease the growth rate of R. stolonifer . We evaluated the honey with a zone of inhibition (ZOI) test on agar plates. Sabouraud dextrose agar was mixed with differing volumes of honey to generate concentrations between 10.0% and 30.0%. These plates were then inoculated with a solution of spores collected from the mold. The ZOI was measured to determine antifungal effectiveness. A statistically significant difference was found between the means of all concentrations except for 20.0% and 22.5%. Our findings support the hypothesis as we showed a positive correlation between the honey concentration and growth rate of mold. By using this data, progress could be made on an all-natural, honey-based preservative.