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Testing the Effects of Resveratrol, Apigenin, and Glucosamine to Effectively Reduce Prostate Cancer Cell Proliferation, Migration Levels, and Increase Apoptosis

Yang et al. | Apr 16, 2020

Testing the Effects of Resveratrol, Apigenin, and Glucosamine to Effectively Reduce Prostate Cancer Cell Proliferation, Migration Levels, and Increase Apoptosis

The current five-year survival rate of metastasized prostate cancer is only 30% and occurs in every one in nine men. Researchers have shown that people with a type of dwarfism called Laron’s Syndrome are immune to cancer due to their low levels of insulin-like growth factor-1 (IGF-1). For this reason, experimentally modifying the level of IGF-1 could provide better insight into whether lowering the levels of IGF-1 in prostate cancer cell lines (e.g. PC-3) could be an effective treatment to reduce their rates of proliferation and migration and increase apoptosis. We selected three compounds, which researchers have shown decrease IGF-1 levels, to test and combine to determine which is the most promising.

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Evaluation of Tea Extract as an Inhibitor of Oxidative Stress in Prostate Cells

Zhang et al. | Jan 22, 2019

Evaluation of Tea Extract as an Inhibitor of Oxidative Stress in Prostate Cells

One important factor that contributes to human cancers is accumulated damage to cells' DNA due to the oxidative stress caused by free radicals. In this study, the authors investigate the effects of several different tea leaf extracts on oxidative stress in cultured human prostate cells to see if antioxidants in the tea leaves could help protect cells from this type of DNA damage. They found that all four types of tea extract (as well as direct application of the antioxidant EGCG) improved the outcomes for the cultured cells, with white tea extract having the strongest effect. This research suggests that tea extracts and the antioxidants that they contain may have applications in the treatment of the many diseases associated with cellular DNA damage, including cancer.

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The Effect of Music on Heart Rate

Agrawal et al. | Apr 25, 2013

The Effect of Music on Heart Rate

Different songs can seem to evoke different emotions. Here the authors demonstrate that different songs can have a significant effect on the heart rate of listeners. A slower song slows heart rate, and a faster song increases it.

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