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Testing HCN1 channel dysregulation in the prefrontal cortex using a novel piezoelectric silk neuromodulator

Mathew et al. | May 05, 2021

Testing HCN1 channel dysregulation in the prefrontal cortex using a novel piezoelectric silk neuromodulator

Although no comprehensive characterization of schizophrenia exists, there is a general consensus that patients have electrical dysfunction in the prefrontal cortex. The authors designed a novel piezoelectric silk-based implant and optimized electrical output through the addition of conductive materials zinc oxide (ZnO) and aluminum nitride (AlN). With further research and compatibility studies, this implant could rectify electrical misfiring in the infralimbic prefrontal cortex.

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Risk assessment modeling for childhood stunting using automated machine learning and demographic analysis

Sirohi et al. | Sep 25, 2022

Risk assessment modeling for childhood stunting using automated machine learning and demographic analysis

Over the last few decades, childhood stunting has persisted as a major global challenge. This study hypothesized that TPTO (Tree-based Pipeline Optimization Tool), an AutoML (automated machine learning) tool, would outperform all pre-existing machine learning models and reveal the positive impact of economic prosperity, strong familial traits, and resource attainability on reducing stunting risk. Feature correlation plots revealed that maternal height, wealth indicators, and parental education were universally important features for determining stunting outcomes approximately two years after birth. These results help inform future research by highlighting how demographic, familial, and socio-economic conditions influence stunting and providing medical professionals with a deployable risk assessment tool for predicting childhood stunting.

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Functional Network Connectivity: Possible Biomarker for Autism Spectrum Disorders (ASD)

Wang et al. | Feb 23, 2015

Functional Network Connectivity: Possible Biomarker for Autism Spectrum Disorders (ASD)

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder and is difficult to diagnose in young children. Here magnetoencephalography was used to compare the brain activity in patients with ASD to patients in a control group. The results show that patients with ASD have a high level of activity in different areas of the brain than those in the control group.

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The influence of working memory on auditory category learning in the presence of visual stimuli

Vishag et al. | Sep 18, 2022

The influence of working memory on auditory category learning in the presence of visual stimuli

Here in an effort to better understand how our brains process and remember different categories of information, the authors assessed working memory capacity using an operation span task. They found that individuals with higher working memory capacity had higher overall higher task accuracy regardless of the type of category or the type of visual distractors they had to process. They suggest this may play a role in how some students may be less affected by distracting stimuli compared to others.

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Herbal Extracts Alter Amyloid Beta Levels in SH-SY5Y Neuroblastoma Cells

Xu et al. | Feb 25, 2020

Herbal Extracts Alter Amyloid Beta Levels in SH-SY5Y Neuroblastoma Cells

Alzheimer’s disease (AD) is a type of dementia that affects more than 5.5 million Americans, and there are no approved treatments that can delay the advancement of the disease. In this work, Xu and Mitchell test the effects of various herbal extracts (bugleweed, hops, sassafras, and white camphor) on Aβ1-40 peptide levels in human neuroblastoma cells. Their results suggest that bugleweed may have the potential to reduce Aβ1-40 levels through its anti-inflammatory properties.

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Analysis of the Exoplanet HD 189733b to Confirm its Existence

Babaria et al. | Sep 21, 2020

Analysis of the Exoplanet HD 189733b to Confirm its Existence

In this study, the authors study features of exoplanet 189733 b. This exoplanet, or planets that orbit stars other than the Sun, is found in the HD star system. Using a DSLR camera, they constructed a high caliber exoplanet transit detection tracker to study the orbital periods, radial velocity, and photometry of 189733 b. They then compared results from their system to data collected by other high precision studies. What they found was that their system produced results supporting previously published studies. These results are exciting results from the solar system demonstrating the importance of validating radial velocity and photometry data using high-precision studies.

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A novel encoding technique to improve non-weather-based models for solar photovoltaic forecasting

Ahmed et al. | Jun 09, 2023

A novel encoding technique to improve non-weather-based models for solar photovoltaic forecasting

Several studies have applied different machine learning (ML) techniques to the area of forecasting solar photovoltaic power production. Most of these studies use weather data as inputs to predict power production; however, there are numerous practical issues with the procurement of this data. This study proposes models that do not use weather data as inputs, but rather use past power production data as a more practical substitute to weather-based models. Our proposed models demonstrate a better, cheaper, and more reliable alternatives to current weather models.

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The Impact of the COVID-19 Pandemic on Mental Health of Teens

Qureshi et al. | Nov 19, 2020

The Impact of the COVID-19 Pandemic on Mental Health of Teens

In this study, the authors investigate whether the COVID-19 pandemic is affecting the mental health of teens. Using data from a study done in Islamabad, Pakistan, the authors find that many teens between the ages of 13 and 19 show signs of mental illness. This study reports important data regarding the mental health of youth and points toward an increased need to address this topic during the pandemic.

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