The authors test the antiproliferative and apoptosis-inducing properties of an extract created from a traditional Indian medicinal plant of the Amaranthus genus.

The authors set out to develop an electrochemical device that would have efficient and sustained carbon dioxide capture.

Glioblastoma Multiforme (GBM) is the most malignant brain tumor with the highest fraction of genome alterations (FGA), manifesting poor disease-free status (DFS) and overall survival (OS). We explored The Cancer Genome Atlas (TCGA) and cBioportal public dataset- Firehose legacy GBM to study DNA repair genes Activating Signal Cointegrator 1 Complex Subunit 3 (ASCC3) and Alpha-Ketoglutarate-Dependent Dioxygenase AlkB Homolog 3 (ALKBH3). To test our hypothesis that these genes have correlations with FGA and can better determine prognosis and survival, we sorted the dataset to arrive at 254 patients. Analyzing using RStudio, both ASCC3 and ALKBH3 demonstrated hypomethylation in 82.3% and 61.8% of patients, respectively. Interestingly, low mRNA expression was observed in both these genes. We further conducted correlation tests between both methylation and mRNA expression of these genes with FGA. ASCC3 was found to be negatively correlated, while ALKBH3 was found to be positively correlated, potentially indicating contrasting dysregulation of these two genes. Prognostic analysis showed the following: ASCC3 hypomethylation is significant with DFS and high ASCC3 mRNA expression to be significant with OS, demonstrating ASCC3’s potential as disease prediction marker.

In this study, the authors identify transcripts and gene networks that are changed after infection with the Middle East Respiratory Syndrome-related coronavirus (MERS-CoV).

Recognizing the need for a method to filter microplastics from polluted water the authors sought to use nonpolar solvents, palm oil and palm kernel oil, to filter microplastics out of model seawater. By relying on the separation of polar and nonpolar solvents followed by freezing the nonpolar solvent, they reported that microplastics could be extracted with percentages ranging from 96.2% to 94.2%. They also provided an estimation to use this method as part of container ships to clean the Pacific Ocean of microplastics.

In this study, the authors design a series of new biaryl small molecules to target and block the binding pocket of the enzyme dihydropteroate synthase, which is important for prokaryotic biosynthesis of folic acid and could serve as better antimicrobial compounds.

In this article, the authors use datasets of professional and youth soccer players' movements to map and statistically compare them. Analysis compared movements that led to goals or no-goals and differences between pros and youth.

Solar and radio frequency harvesters serve as a viable alternative energy source to batteries in many cases where the battery cannot be easily replaced. Using specifically designed circuit models, the authors quantify the reliability of different harvested energy sources to identify the most practical and efficient forms of renewable energy.

Social media usage is predicted to impact teen well-being and emotional status. This study sought to assess the impact of teen technology usage on their social lives. Surveys of 8th and 9th graders were used to assess compare technology usage between males and females as well as and how social media usage impacts the perception of social environment at school.

In a 10-year period in the early 2000’s, hospital-based (nosocomial) infections increased by 123%, and this number is increasing as time goes on. The purpose of this experiment was to use hyaluronic acid, silver nanoparticles, and a bacteriophage cocktail to create a hydrogel that promotes wound healing by increasing cell proliferation while simultaneously disrupting biofilm formation and breaking down Staphylococcus aureus and Pseudomonas aeruginosa, which are two strains of bacteria that attribute to nosocomial infections and are increasing in antibiotic resistance.