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Phospholipase A2 increases the sensitivity of doxorubicin induced cell death in 3D breast cancer cell models

Lee et al. | Mar 30, 2022

Phospholipase A2 increases the sensitivity of doxorubicin induced cell death in 3D breast cancer cell models

Inefficient penetration of cancer drugs into the interior of the three-dimensional (3D) tumor tissue limits drugs' delivery. The authors hypothesized that the addition of phospholipase A2 (PLA2) would increase the permeability of the drug doxorubicin for efficient drug penetration. They found that 1 mM PLA2 had the highest permeability. Increased efficiency in drug delivery would allow lower concentrations of drugs to be used, minimizing damage to normal cells.

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Utilizing a Wastewater-Based Medium for Engineered Saccharomyces cerevisiae for the Biological Production of Fatty Alcohols and Carboxylic Acids to Replace Petrochemicals

Ramesh et al. | Oct 02, 2019

Utilizing a Wastewater-Based Medium for Engineered <em>Saccharomyces cerevisiae</em> for the Biological Production of Fatty Alcohols and Carboxylic Acids to Replace Petrochemicals

Saccharomyces cerevisiae yeast is used to produce bioethanol, an alternative to fossil fuels. In this study, authors take advantage of this well studied yeast by genetically engineering them to increase fatty acid biosynthesis and culturing in a cost-effective wastewater based medium; potentially providing a sustainable alternative to petrochemicals.

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Optimizing Interplanetary Travel Using a Genetic Algorithm

Murali et al. | Oct 28, 2018

Optimizing Interplanetary Travel Using a Genetic Algorithm

In this work, the authors develop an algorithm that solves the problem of efficient space travel between planets. This is a problem that could soon be of relevance as mankind continues to expand its exploration of outer space, and potentially attempt to inhabit it.

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Correlation of Prominent Intelligence Type & Coworker Relations

Rasmus et al. | Mar 29, 2022

Correlation of Prominent Intelligence Type & Coworker Relations

Ashley Moulton & Joseph Rasmus investigate 9 controversial categories of intelligence as predicted by Multiple Intelligence Theory, originally proposed in the mid-1980s. By collecting data from 56 participants, they record that there may not actually be a correlation between these categorical types when it comes to workplace atmosphere and project efficiency.

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Differences in Reliability and Predictability of Harvested Energy from Battery-less Intermittently Powered Systems

Sampath et al. | Apr 29, 2020

Differences in Reliability and Predictability of Harvested Energy from Battery-less Intermittently Powered Systems

Solar and radio frequency harvesters serve as a viable alternative energy source to batteries in many cases where the battery cannot be easily replaced. Using specifically designed circuit models, the authors quantify the reliability of different harvested energy sources to identify the most practical and efficient forms of renewable energy.

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A Scientific Investigation of Alternative Growing Methods to Cultivate Lactuca sativa

Fishback et al. | Apr 23, 2020

A Scientific Investigation of Alternative Growing Methods to Cultivate Lactuca sativa

In this article, the authors compare different resource-efficient farming methods for the vegetable Lactuca sativa. They compared hydroponics (solid growth medium with added nutrients) to aquaponics (water with fish waste to provide nutrients) and determined efficacy by measuring plant height over time. While both systems supported plant growth, the authors concluded that aquaponics was the superior method for supporting Lactuca sativa growth. These findings are of great relevance as we continue to find the most sustainable and efficient means for farming.

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Optimizing airfoil shape for small, low speed, unmanned gliders: A homemade investigation

Lara et al. | Mar 30, 2023

Optimizing airfoil shape for small, low speed, unmanned gliders: A homemade investigation
Image credit: Konrad Wojciechowski

Here, the authors sought to identify a method to optimize the lift generated by an airfoil based solely on its shape. By beginning with a Bernoullian model to predict an optimized wing shape, the authors then tested their model against other possible shapes by constructing them from Styrofoam and testing them in a small wind tunnel. Contrary to their hypothesis, they found their expected optimal airfoil shape did not result in the greatest lift generation. They attributed this to a variety of confounding variables and concluded that their results pointed to a correlation between airfoil shape and lift generation.

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