In this study, the authors analyze gene expression datasets to determine if there is a core set of genes dysregulated during nonalcoholic steatohepatitis.
Read More...Identification of a core set of model agnostic mRNA associated with nonalcoholic steatohepatitis (NASH)
In this study, the authors analyze gene expression datasets to determine if there is a core set of genes dysregulated during nonalcoholic steatohepatitis.
Read More...Examining the relationship between screen time and achievement motivation in an adolescent population
In this study, the authors conduct a survey of high school students to evaluate the effects of screen time and habits on motivation.
Read More...Heat conduction: Mathematical modeling and experimental data
In this experiment, the authors modify the heat equation to account for imperfect insulation during heat transfer and compare it to experimental data to determine which is more accurate.
Read More...The Development of a Highly Sensitive Home Diagnosis Kit for Group A Streptococcus Bacteria (GAS)
In this article, Mai et al. have developed a do-it-yourself kit for the detection of Strep A bacterial infections. While Strep A infections require antibiotic administration, viral infections, which can present with similar symptoms, often resolve on their own. The problem with delayed antibiotic treatment is an increasing risk of complications. Currently an accurate diagnosis requires that patients make the trip to the hospital where sensitive tests can be performed. The method described here, bundled into a commercially available kit, could help speed up the identification of such bacterial infections. When presented with symptoms of a sore throat and fever, you could just buy the kit at your local pharmacy, perform the simple yet highly accurate and sensitive test, and know whether an urgent trip to the doctor's for an antibiotic prescription is necessary. How convenient!
Read More...Breast cancer mammographic screening by different guidelines among women of different races/ethnicities
Mammographic screening is a common diagnostic tool for breast cancer among average-risk women. The authors hypothesized that adherence rates for mammographic screening may be lower among minorities (non-Hispanic black (NHB) and Hispanic/Latino) than among non-Hispanic whites (NHW) regardless of the guideline applied. The findings support other studies’ results that different racial/ethnic and socio-demographic factors can affect screening adherence. Therefore, healthcare providers should promote breast cancer screening especially among NHW/Hispanic women and women lacking insurance coverage.
Read More...Cocktail therapy to inhibit multispecies biofilm in cystic fibrosis patients
Here, recognizing the important role of bacterial biofilms in many life-threatening chronic infections, the authors investigated the effectiveness of a combination treatment on biofilms composed of up to three different common species within the lungs of cystic fibrosis patients with computational analysis. They found that a triple cocktail therapy targeting three different signaling pathways has significant potential as both a treatment and prophylaxis.
Read More...Gene expression profiling of MERS-CoV-London strain
In this study, the authors identify transcripts and gene networks that are changed after infection with the Middle East Respiratory Syndrome-related coronavirus (MERS-CoV).
Read More...The Effect of Lyrical and Instrumental Music on Reading Comprehension Tasks
Herring and Scott investigated how specific types of background music affected 8th and 9th graders' performance on a reading comprehension task. In the study, their results indicated that music with English lyrics led to lower reading comprehension scores, while foreign language and instrumental music was comparable to no music at all. The authors therefore recommend that teachers avoid playing English language music for students completing reading tasks in order to minimize distractions and improve work efficiency.
Read More...Zinc-related Treatments Combined with Chloroquine and Gemcitabine for Treating Pancreatic Cancer
Pancreatic cancer is one of the deadliest cancers, with a 10% 5-year survival rate. The authors studied various dosages of TPEN and zinc in combination with Chloroquine and Gemcitabine as treatments to reduce cell proliferation. Results showed that when combined with Chloroquine and Gemcitabine, zinc and TPEN both significantly lowered cell proliferation compared to Gemcitabine, suggesting a synergistic effect that resulted in a more cytotoxic treatment. Further research and clinical trials on this topic are needed to determine whether this could be a viable treatment for pancreatic cancer.
Read More...Phytochemical analysis of Annona Reticulata extract and an in-vitro study on its anti-proliferative effects
In this study, the authors investigate the anti-cancer effects of Annona Reticulata (Ramphal or custard apple) by testing whether its extract could inhibit HeLa cell viability.
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