![Discovery of novel targets for diffuse large B-cell lymphoma](/rails/active_storage/representations/proxy/eyJfcmFpbHMiOnsibWVzc2FnZSI6IkJBaHBBclVKIiwiZXhwIjpudWxsLCJwdXIiOiJibG9iX2lkIn19--9c4e5b549a0a0734fc563524576786fc9c7ff799/eyJfcmFpbHMiOnsibWVzc2FnZSI6IkJBaDdCem9MWm05eWJXRjBTU0lJY0c1bkJqb0dSVlE2QzNKbGMybDZaVWtpRFRZd01IZzJNREErQmpzR1ZBPT0iLCJleHAiOm51bGwsInB1ciI6InZhcmlhdGlvbiJ9fQ==--33b2b080106a274a4ca568f8742d366d42f20c14/Figure5.png)
In this study, the authors identify new potential targets to treat advanced diffuse large B-cell lymphoma after treatment relapse and loss of CD19 expression.
Read More...Discovery of novel targets for diffuse large B-cell lymphoma
In this study, the authors identify new potential targets to treat advanced diffuse large B-cell lymphoma after treatment relapse and loss of CD19 expression.
Read More...Plasmid Variance and Nutrient Regulation of Bioluminescence Genes
Numerous organisms, including the marine bacterium Aliivibrio fischeri, produce light. This bioluminescence is involved in many important symbioses and may one day be an important source of light for humans. In this study, the authors investigated ways to increase bioluminescence production from the model organism E. coli.
Read More...Simulation of cosmic rays in the presence of a magnetic field
In this study the authors looked the trajectories of cosmic rays moving through a dipole field. They found that the trajectories of cosmic rays are determined by a particle's energy and interaction with Earth's B field.
Read More...Comparing the Effectiveness of Popular Treatments for Swelling and Scarring
Numerous specialty treatments claim to reduce swelling and scarring; however, it is unknown if these treatments are more effective than less expensive treatments. In an attempt to determine if one outperforms the other, treatments were applied to the same subject following bilateral orthopedic foot surgery. No difference was found the specialty treatments compared to more cost-effective treatments.
Read More...Focusing Sound Waves Using a Two-Dimensional Non-Linear System
Sound waves can be amazingly powerful, especially when they work together. Here the authors create an “acoustic lens” that focuses sound waves on a single location. This makes the sound waves very powerful, capable of causing damage at a precise point. In the future, acoustic lenses like this could potentially be used to treat cancer by killing small tumors without surgery.
Read More...A novel calibration algorithm and its effects on heading measurement accuracy of a low-cost magnetometer
Digital compasses are essential in technology that we use in our everyday lives: phones, vehicles, and more. Li and Liu address the accuracy of these devices by presenting a new algorithm for accurately calibrating low-cost magnetometers.
Read More...Analysis of complement system gene expression and outcome across the subtypes of glioma
Here the authors sought to better understand glioma, cancer that occurs in the glial cells of the brain with gene expression profile analysis. They considered the expression of complement system genes across the transcriptional and IDH-mutational subtypes of low-grade glioma and glioblastoma. Based on their results of their differential gene expression analysis, they found that outcomes vary across different glioma subtypes, with evidence suggesting that categorization of the transcriptional subtypes could help inform treatment by providing an expectation for treatment responses.
Read More...Application of gene therapy for reversing T-cell dysfunction in cancer
Since cancer cells inhibit T-cell activity, the authors investigated a method to reverse T-cell disfunction with gene therapy, so that the T-cells would become effective once again in fighting cancer cells. They used the inhibition of proprotein convertases (PCSK1) in T cells and programmed death-ligand 1 (CD274) in cancer cells. They observed the recovery of IL-2 expression in Jurkat cells, with increased recovery noted in a co-culture sample. This study suggests a novel strategy to reactivate T cells.
Read More...Efficacy of Mass Spectrometry Versus 1H Nuclear Magnetic Resonance With Respect to Denaturant Dependent Hydrogen-Deuterium Exchange in Protein Studies
The misfolding of proteins leads to numerous diseases including Akzheimer’s, Parkinson’s and Type II Diabetes. Understanding of exactly how proteins fold is crucial for many medical advancements. Chenna and Englander addressed this problem by measuring the rate of hydrogen-deuterium exchange within proteins exposed to deuterium oxide in order to further elucidate the process of protein folding. Here, mass spectrometry was used to measure exchange in Cytochrome c and was compared to archived 1H NMR data.
Read More...Can essential oils be allelopathic to Lolium multiforum without harming Solanum lycopersicum?
Seeking to investigate eco-friendly biological methods to control weeds and enhance food crop yields, here the authors considered the effects of three essential oils on seed germination and radicle length of both a weed and a common crop. They found that treatment with turmeric oil had phytotoxic potential, leading to a reduction in both seed germination and radicle length of the weed. In contrast, ginger oil possessed allelopathic properties towards both. The authors suggest that essential oils could be used as eco-friendly bio-herbicides.
Read More...Search articles by title, author name, or tags